Evidence map›Paper›PMID 31863221›Full record

ArticleCellular and molecular neurobiology2020

Single-Cell Analysis for Glycogen Localization and Metabolism in Cultured Astrocytes.

Yuanyuan Zhu, Ze Fan, Rui Wang, Rougang Xie, Haiyun Guo, Ming Zhang, Baolin Guo, Tangna Sun, Haifeng Zhang, Lixia Zhuo and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Cellular and molecular neurobiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Yuanyuan Zhu *Department of Neurobiology, The School of Basic Medicine, The Fourth Military Medical University, Xi'an, China.
Ze Fan *Department of Anesthesiology and Perioperative Medicine, Xijing Hospital of the Fourth Military Medical University, Xi'an, China.
Rui Wang *Department of Neurobiology, The School of Basic Medicine, The Fourth Military Medical University, Xi'an, China.
Rougang XieDepartment of Neurobiology, The School of Basic Medicine, The Fourth Military Medical University, Xi'an, China.
Haiyun GuoDepartment of Anesthesiology and Perioperative Medicine, Xijing Hospital of the Fourth Military Medical University, Xi'an, China.
Ming ZhangDepartment of Neurobiology, The School of Basic Medicine, The Fourth Military Medical University, Xi'an, China.
Baolin GuoDepartment of Neurobiology, The School of Basic Medicine, The Fourth Military Medical University, Xi'an, China.
Tangna SunDepartment of Neurobiology, The School of Basic Medicine, The Fourth Military Medical University, Xi'an, China.
Haifeng ZhangDepartment of Neurobiology, The School of Basic Medicine, The Fourth Military Medical University, Xi'an, China.
Lixia ZhuoCenter for Brain Science, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Yan LiCenter for Brain Science, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China. liyanxjtu@xjtu.edu.cn.ORCID http://orcid.org/0000-0002-7465-7705
Shengxi WuDepartment of Neurobiology, The School of Basic Medicine, The Fourth Military Medical University, Xi'an, China. shengxi@fmmu.edu.cn.ORCID http://orcid.org/0000-0002-3210-9567
Air Force Medical University · CNFirst Affiliated Hospital of Xi'an Jiaotong University · CNXijing Hospital · CN

Funding

Innovation Teams in Priority Areas Accredited by the Ministry of Science and Technology 2014RA4029Natural Science Foundation of China 81671184Natural Science Foundation of China 81730035Natural Science Foundation of China 81870867
6 · The paper itself

Abstract

Cerebral glycogen is principally localized in astrocytes rather than in neurons. Glycogen metabolism has been implicated in higher brain functions, including learning and memory, yet the distribution patterns of glycogen in different types of astrocytes have not been fully described. Here, we applied a method based on the incorporation of 2-NBDG, a D-glucose fluorescent derivative that can trace glycogen, to investigate glycogen's distribution in the brain. We identified two types of astrocytes, namely, 2-NBDG

Indexed as

4-Chloro-7-nitrobenzofurazanAnimalsAstrocytesCells, CulturedCerebral CortexDeoxyglucoseGlucoseGlycogenMiceMice, Inbred C57BLNeuronsSingle-Cell Analysis2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose4-Chloro-7-nitrobenzofurazanDeoxyglucoseGlucoseGlycogenAstrocytesFibrous astrocyteGlycogenGlycogen metabolismProtoplasmic astrocyteSingle-cell PCR

Identifiers

PMID31863221
PMCPMC7261284
OpenAlexW2995821584

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.