Evidence map›Paper›PMID 31863182›Full record

ArticleEuropean child & adolescent psychiatry2020

Maternal personality traits moderate treatment response in the Multimodal Treatment Study of attention-deficit/hyperactivity disorder.

Guillermo Perez Algorta, Heather A MacPherson, L Eugene Arnold, Stephen P Hinshaw, Lily Hechtman, Margaret H Sibley, Elizabeth B Owens

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European child & adolescent psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 78% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 3 countries.

Guillermo Perez AlgortaLA14YG, Lancaster University, Furness C73, Lancaster, UK. g.perezalgorta@lancaster.ac.uk.ORCID http://orcid.org/0000-0001-6610-4951
Heather A MacPhersonBrown University, Providence, RI, USA.
L Eugene ArnoldThe Ohio State University, Columbus, OH, USA.
Stephen P HinshawUniversity of California, Berkeley, CA, USA.
Lily HechtmanMcGill University, Montreal, Canada.
Margaret H SibleyUniversity of Washington, Seattle, WA, USA.
Elizabeth B OwensUniversity of California, Berkeley, CA, USA.
University of California, Berkeley · USBrown University · USLancaster University · GBMcGill University · CAThe Ohio State University · USUniversity of Washington · US

Funding

MULTISITE MULTIMODALITY TREATMENT STUDY OF ADHD/ADDU01MH050440 · NIMH · UNIVERSITY OF CALIFORNIA IRVINE · PI SWANSON, JAMES M · 1992 to 2000
$17k
MULTISITE MULTIMODAL TREATMENT STUDY OF ADHD/ADDU01MH050453 · NIMH · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ABIKOFF, HOWARD B · 1992 to 2000
$17k
PHARMACOLOGIC AND PSYCHOSOCIAL INTERVENTIONS FOR ADHDU01MH050461 · NIMH · UNIVERSITY OF CALIFORNIA BERKELEY · PI HINSHAW, STEPHEN P · 1992 to 2000
$17k
PHARMACOLOGICAL AND PSYCHOSOCIAL TREATMENT FOR ADHDU01MH050467 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI PELHAM, WILLIAM E · 1992 to 2000
$17k
NIMH NIH HHS U01 MH050440NIMH NIH HHS U01 MH050453NIMH NIH HHS U01 MH050461NIMH NIH HHS U01 MH050467NIMH NIH HHS U01MH50440NIMH NIH HHS U01 MH50453NIMH NIH HHS U01 MH50461NIMH NIH HHS U01 MH50467NIMH NIH HHS U01 MH50477
6 · The paper itself

Abstract

Some mothers of children with attention-deficit/hyperactivity disorder (ADHD) present with maladaptive personality profiles (high neuroticism, low conscientiousness). The moderating effect of maternal personality traits on treatment outcomes for childhood ADHD has not been examined. We evaluate whether maternal neuroticism and conscientiousness moderated response in the Multimodal Treatment Study of Children with ADHD. This is one of the first studies of this type. In a randomized controlled trial (RCT), 579 children aged 7-10 (M = 8.5); 19.7% female; 60.8% White with combined-type ADHD were randomly assigned to systematic medication management (MedMgt) alone, comprehensive multicomponent behavioral treatment (Beh), their combination (Comb), or community comparison treatment-as-usual (CC). Latent class analysis and linear mixed effects models included 437 children whose biological mothers completed the NEO Five-Factor Inventory at baseline. A 3-class solution demonstrated best fit for the NEO: MN&MC = moderate neuroticism and conscientiousness (n = 284); HN&LC = high neuroticism, low conscientiousness (n = 83); LN&HC = low neuroticism, high conscientiousness (n = 70). Per parent-reported symptoms, children of mothers with HN&LC, but not LN&HC, had a significantly better response to Beh than to CC; children of mothers with MN&MC and LN&HC, but not HN&LC, responded better to Comb&MedMgt than to Beh&CC. Per teacher-reported symptoms, children of mothers with HN&LC, but not LN&HC, responded significantly better to Comb than to MedMgt. Children of mothers with high neuroticism and low conscientiousness benefited more from behavioral treatments (Beh vs. CC; Comb vs. MedMgt) than other children. Evaluation of maternal personality may aid in treatment selection for children with ADHD, though additional research on this topic is needed.

Indexed as

AdultAttention Deficit Disorder with HyperactivityChildCombined Modality TherapyFemaleHumansMaleMothersPersonality DisordersTreatment OutcomeAttention-deficit/hyperactivity disorderConscientiousnessMaternal personality traitsNeuroticismTreatment moderator

Identifiers

PMID31863182
PMCPMC7596006
OpenAlexW2996493707

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.