ArticleParasitology research2020
Multiple haplotypes of Echinococcus granulosus sensu stricto in single naturally infected intermediate hosts.
Article in Parasitology research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Echinococcus granulosus sensu lato Genotypes in Different Hosts Worldwide: A Systematic Review.Acta parasitologica · 2022Pooled it
- Article
- Calprotectin Expression in Adventitial Layer of Cattle and SheepInternational journal of molecular sciences · 2025Article
- Molecular epidemiology and phylogenetic analysis of Echinococcus spp. in the Qinghai-Tibetan Plateau: unraveling genetic evolution in a high-risk region for echinococcosis.Veterinary research communications · 2025Article
- γδ T cell distribution in the adventitial layer of non-fertile cystic echinococcosis cysts from cattle livers.Scientific reports · 2025Article
- Molecular identification of zoonotic taeniids metacestodes in several rodent species trapped in Central Europe.Frontiers in veterinary science · 2025Article
- Epidemiology and genetic diversity of Echinococcus granulosus sensu stricto in the East Tianshan Mountains, Xinjiang, China.Parasitology research · 2024Article
- Weighted gene co-expression network analysis reveals immune evasion related genes inExperimental biology and medicine (Maywood, N.J.) · 2024Article
- Molecular Study of Echinococcus granulosus Cestodes in Ukraine and the First Genetic Identification of Echinococcus granulosus Sensu Stricto (G1 Genotype) in the Country.Acta parasitologica · 2022Article
- Transcriptome analysis of Echinococcus granulosus sensu stricto protoscoleces reveals differences in immune modulation gene expression between cysts found in cattle and sheep.Veterinary research · 2022Article
- Phylogenetics and Pathology of Hydatid Disease in Slaughtered Buffaloes of North India.Acta parasitologica · 2021Article
- Response patterns in adventitial layer of Echinococcus granulosus sensu stricto cysts from naturally infected cattle and sheep.Veterinary research · 2021Article
- Article
- Microsatellite Investigations of MultiplePathogens (Basel, Switzerland) · 2020Article
- Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cystic echinococcosis is a disease that affects both humans and animals, caused by cryptic species complex belonging to the platyhelminth Echinococcus granulosus sensu lato (s.l.). This disease is distributed worldwide, with E. granulosus sensu stricto (s.s.) being the most widespread of the species. High genetic variability has been demonstrated within E. granulosus s.s. studying single cyst per infected animal identifying a number of different haplotypes. However, few studies have addressed the genetic diversity of this parasite within a single intermediate host with multiple Echinococcus cysts. To date, it remains unknown if specific haplotypes of E. granulosus s.s. produce differences in biological features of the cyst. Here, we use the full length of the mitochondrial gene cox1 to determine E. granulosus s.s. haplotypes in samples from both cattle and sheep which harboured more than one cyst in different areas in Chile, where this parasite is endemic. We found 16 different haplotypes in 66 echinococcal cysts from 10 animals, and both cattle and sheep can harbour up to five different haplotypes of E. granulosus s.s. in the same animal. Regarding cyst fertility, five animals had both fertile and infertile Echinococcus cysts in both single and multiple haplotype infections. There was no association between haplotype and cyst fertility, size, or adventitial layer characteristics. Sampling and sequencing every Echinococcus cyst found in the intermediate host reveals a high molecular variability. We speculate that multiple haplotype infections could also suggest that intermediate hosts come from hyperendemic areas.
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