ArticleNature communications2019
Relaxed purifying selection in autopolyploids drives transposable element over-accumulation which provides variants for local adaptation.
Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.
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69 citing papers in PubMed, 131 citations in OpenAlex.
- Investigation of allele-specific expression in citrus hybrids reveals the association between siRNA-mediatedHorticulture research · 2026Article
- Transposable Element Dynamics Drive the Genomic Evolution and Phenotypic Diversification of Allotetraploid Common Carp.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Somatic genome-doubling is the most parsimonious route to allopolyploidy.The New phytologist · 2026Review
- Genomic and Ecological Flexibility Shape the Global Distribution of a Black Fungus.Environmental microbiology · 2026Article
- The jujube pan-TE map identifies transposable element insertions associated with domestication and pericarp development.Horticulture research · 2026Article
- Population genomics reveals association of transposable elements variants with climatic adaptation in wild Amur grape.Nature communications · 2026Article
- Evolutionary history and genomic consequences of polyploidization in natural populations ofHorticulture research · 2026Article
- Structural variation drives rhizome innovation and adaptive divergence in sister Medicago species.Journal of integrative plant biology · 2026Article
- Chromosome-scale Genome Assembly of the Most Abundant Ectomycorrhizal Fungus Cenococcum Geophilum Reveals Massive TE Expansion and RIP Defense Mechanism.Genome biology and evolution · 2026Article
- Diploid origins and early genome stabilization in the allotetraploid Arabidopsis suecica.The New phytologist · 2026Article
- Medicago super-pangenome reveals adaptive advantages and evolutionary constraints in autotetraploid alfalfa.Nature communications · 2025Article
- Whole-Genome Sequence of Potamopyrgus antipodarum-A Model System for the Maintenance of Sexual Reproduction-Reveals a Recent Whole-Genome Duplication.Genome biology and evolution · 2025Article
- Transposon Dynamics Drive Genome Evolution and Regulate Genetic Mechanisms of Agronomic Traits in Cotton.Plants (Basel, Switzerland) · 2025Article
- Comprehensive transposon-insertion profiling unravels the asexual breeding history of sweet orange cultivars.Plant communications · 2025Article
- Whole-genome duplication increases genetic diversity and load in outcrossingProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Transposable elements drive the subgenomic divergence of homoeologous genes to shape wheat domestication and improvement.Plant communications · 2025Article
- Relaxed Purifying Selection is Associated with an Accumulation of Transposable Elements in Flies.Molecular biology and evolution · 2025Article
- Ecological Niche Adaptations Influence Transposable Element Dynamics in Pollinating and Non-Pollinating Fig Wasps.Ecology and evolution · 2025Article
- Genome-Wide Identification and Functional Analysis ofInternational journal of molecular sciences · 2025Article
- Parallel Selection in Domesticated Atlantic Salmon from Divergent Founders Including on Whole-Genome Duplication-derived Homeologous Regions.Genome biology and evolution · 2025Article
9 more citing papers are in PubMed but not listed here.
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Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Polyploidization is frequently associated with increased transposable element (TE) content. However, what drives TE dynamics following whole genome duplication (WGD) and the evolutionary implications remain unclear. Here, we leverage whole-genome resequencing data available for ~300 individuals of Arabidopsis arenosa, a well characterized natural diploid-autotetraploid plant species, to address these questions. Based on 43,176 TE insertions we detect in these genomes, we demonstrate that relaxed purifying selection rather than transposition bursts is the main driver of TE over-accumulation after WGD. Furthermore, the increased pool of TE insertions in tetraploids is especially enriched within or near environmentally responsive genes. Notably, we show that the major flowering-time repressor gene FLC is disrupted by a TE insertion specifically in the rapid-cycling tetraploid lineage that colonized mainland railways. Together, our findings indicate that tetrasomy leads to an enhanced accumulation of genic TE insertions, some of which likely contribute to local adaptation.
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