Evidence map›Paper›PMID 31862799›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2020

Reinier Hernandez, Joseph J Grudzinski, Eduardo Aluicio-Sarduy, Christopher F Massey, Anatoly N Pinchuk, Ariana N Bitton, Ravi Patel, Ray Zhang, Aakarsha V Rao, Gopal Iyer and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Enhanced Antitumor Efficacy ofInternational journal of radiation oncology, biology, physics · 2026
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  15. Molecules (Basel, Switzerland) · 2024
    Article
  16. Immunological effects of radiopharmaceutical therapy.Frontiers in nuclear medicine · 2024
    Review
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Reinier HernandezDepartment of Radiology, University of Wisconsin-Madison, Madison, Wisconsin hernandez6@wisc.edu.
Joseph J GrudzinskiDepartment of Radiology, University of Wisconsin-Madison, Madison, Wisconsin.
Eduardo Aluicio-SarduyDepartment of Medical Physics, University of Wisconsin-Madison, Madison, Wisconsin.
Christopher F MasseyDepartment of Radiology, University of Wisconsin-Madison, Madison, Wisconsin.
Anatoly N PinchukDepartment of Radiology, University of Wisconsin-Madison, Madison, Wisconsin.
Ariana N BittonDepartment of Radiology, University of Wisconsin-Madison, Madison, Wisconsin.
Ravi PatelDepartment of Human Oncology, University of Wisconsin-Madison, Madison, Wisconsin; and.
Ray ZhangDepartment of Radiology, University of Wisconsin-Madison, Madison, Wisconsin.
Aakarsha V RaoDepartment of Human Oncology, University of Wisconsin-Madison, Madison, Wisconsin; and.
Gopal IyerDepartment of Human Oncology, University of Wisconsin-Madison, Madison, Wisconsin; and.
Jonathan W EngleDepartment of Medical Physics, University of Wisconsin-Madison, Madison, Wisconsin.
Jamey P WeichertDepartment of Radiology, University of Wisconsin-Madison, Madison, Wisconsin.
University of Wisconsin–Madison · USUniversity of Wisconsin Carbone Cancer Center · US

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI AMY TRENTHAM-DIETZ · 1985 to 2026
$142.6M
U.W. RADIOLOGICAL SCIENCES TRAINING PROGRAMT32CA009206 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Bryan Patrick Bednarz · 1985 to 2026
$12.1M
INTEGRATED TRAINING FOR PHYSICIAN-SCIENTISTST32GM008692 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI BURKARD, MARK E · 1998 to 2020
$10.3M
Immunomodulation of the Tumor Microenvironment with Molecular Targeted Radiotherapy to Facilitate an Adaptive Anti-Tumor Immune Response to Combined Modality ImmunotherapiesU01CA233102 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI MORRIS, ZACHARY SCOTT, WEICHERT, JAMEY P · 2018 to 2022
$4.0M
Utilization of molecular targeted radionuclides to prime immune responses at local and distant metastatic tumor sitesK08CA241319 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI PATEL, RAVI BHASKER · 2019 to 2023
$629k
NCI NIH HHS K08 CA241319NCI NIH HHS P30 CA014520NCI NIH HHS T32 CA009206NCI NIH HHS U01 CA233102NIGMS NIH HHS T32 GM008692
6 · The paper itself

Abstract

There is a clinically unmet need for effective treatments for triple-negative breast cancer (TNBC), as it remains the most aggressive subtype of breast cancer. Herein, we demonstrate a promising strategy using a tumor-targeting alkylphosphocholine (NM600) for targeted radionuclide therapy of TNBC.

Indexed as

AnimalsCell Line, TumorDisease Models, AnimalLutetiumMicePositron Emission Tomography Computed TomographyRadiochemistryRadioisotopesRadiometrySurvival AnalysisTissue DistributionTriple Negative Breast NeoplasmsLutetiumRadioisotopes177Lu-NM600targeted radionuclide therapytheranosticsTNBCtriple-negative breast cancer

Identifiers

PMID31862799
PMCPMC7413241
OpenAlexW2996516775

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.