Evidence map›Paper›PMID 31862736›Full record

ArticleBMJ open2019

Do pharmacy intervention reports adequately describe their interventions? A template for intervention description and replication analysis of reports included in a systematic review.

Mícheál de Barra, Claire Scott, Marie Johnston, M De Bruin, Neil Scott, Catriona Matheson, Christine Bond, Margaret Watson

Registry-linked trialAbstract read
In one paragraph

Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05348538 (Feasibility Study of the Medication Review With Follow up Service for Patients With Polypharmacy in Swiss Community Pharmacies), which is not on this map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05348538 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Feasibility Study of the Medication Review With Follow up Service for Patients With Polypharmacy in Swiss Community Pharmacies

TypeinterventionalSponsorCenter for Primary Care and Public Health (Unisante), University of Lausanne, SwitzerlandRan2023 to 2024Enrolled162ConditionsChronic DiseaseArmsMedication review with follow up or MaJ? for the acronym in french
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mícheál de BarraLife Sciences, Brunel University London, Middlesex, UK micheal.debarra@brunel.ac.uk.ORCID 0000-0003-4455-6214
Claire ScottThe Institute of Applied Health Sciences, University of Aberdeen, Aberdeen, UK.
Marie JohnstonThe Institute of Applied Health Sciences, University of Aberdeen, Aberdeen, UK.
M De BruinThe Institute of Applied Health Sciences, University of Aberdeen, Aberdeen, UK.
Neil ScottThe Institute of Applied Health Sciences, University of Aberdeen, Aberdeen, UK.
Catriona MathesonFaculty of Social Sciences, University of Stirling, Stirling, UK.
Christine BondThe Institute of Applied Health Sciences, University of Aberdeen, Aberdeen, UK.
Margaret WatsonThe Institute of Applied Health Sciences, University of Aberdeen, Aberdeen, UK.ORCID 0000-0002-8198-9273

Funding

Chief Scientist Office CZH/4/1041
6 · The paper itself

Abstract

introductionScientific progress and translation of evidence into practice is impeded by poorly described interventions. The Template for Intervention Description and Replication (TIDieR) was developed to specify the minimal intervention elements that should be reported.

objectives(1) To assess the extent to which outpatient pharmacy interventions were adequately reported. (2) To examine the dimension(s) across which reporting quality varies. (3) To examine trial characteristics that predict better reporting.

methodsThe sample comprised 86 randomised controlled trials identified in a Cochrane review of the effectiveness of pharmacist interventions on patient health outcomes. Duplicate, independent application of a modified 15-item TIDieR checklist was undertaken to assess the intervention reporting. The reporting/non-reporting of TIDieR items was analysed with principal component analysis to evaluate the dimensionality of reporting quality and regression analyses to assess predictors of reporting quality

resultsIn total, 422 (40%) TIDieR items were fully reported, 395 (38%) were partially reported and 231 (22%) were not reported. A further 242 items were deemed not applicable to the specific trials. Reporting quality loaded on one component which accounted for 26% of the variance in TIDieR scores. More recent trials reported a slightly greater number of TIDieR items (0.07 (95% CI 0.02 to 0.13) additional TIDieR items per year of publication). Trials reported an 0.09 (95% CI 0.04 to 0.14) additional TIDieR items per unit increase in impact factor (IF) of the journal in which the main report was published.

conclusionsMost trials lacked adequate intervention reporting. This diminished the applied and scientific value of their research. The standard of intervention reporting is, however, gradually increasing and appears somewhat better in journals with higher IFs. The use of the TIDieR checklist to improve reporting could enhance the utility and replicability of trials, and reduce research waste.

Indexed as

ChecklistHumansPharmaceutical ServicesRandomized Controlled Trials as TopicRegression AnalysisResearch ReportSystematic Reviews as Topicchecklistclinical trials as topic/standardspharmacy/standardsreproducibility of resultsresearch report/standards

Identifiers

PMID31862736
PMCPMC6937059

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.