Evidence map›Paper›PMID 31862696›Full record

ArticleMolecular cancer research : MCR2020

Multi-Omics Analysis Identifies MGA as a Negative Regulator of the MYC Pathway in Lung Adenocarcinoma.

Paula Llabata, Yoichiro Mitsuishi, Peter S Choi, Diana Cai, Joshua M Francis, Manuel Torres-Diz, Namrata D Udeshi, Lior Golomb, Zhong Wu, Jin Zhou and 7 more

Open access · bronzeAbstract read
In one paragraph

Article in Molecular cancer research : MCR, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
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  5. Review
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  7. In vivo CRISPR screens identifyProceedings of the National Academy of Sciences of the United States of America · 2024
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  11. GINS2 promotes the progression of human HNSCC by altering RRM2 expression.Cancer biomarkers : section A of Disease markers · 2024
    Article
  12. Article
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  14. Genomic Characterization of Prostatic Basal Cell Carcinoma.The American journal of pathology · 2023
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Tracing the cis-regulatory changes underlying the endometrial control of placental invasion.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 2 countries.

Paula Llabata *Cancer Epigenetics and Biology Program-PEBC (IDIBELL), Barcelona, Spain.ORCID 0000-0001-7733-6475
Yoichiro Mitsuishi *Department of Medical Oncology, Dana Farber Cancer Institute, Boston, Massachusetts.
Peter S ChoiDepartment of Medical Oncology, Dana Farber Cancer Institute, Boston, Massachusetts.
Diana CaiDepartment of Medical Oncology, Dana Farber Cancer Institute, Boston, Massachusetts.
Joshua M FrancisDepartment of Medical Oncology, Dana Farber Cancer Institute, Boston, Massachusetts.
Manuel Torres-DizCancer Epigenetics and Biology Program-PEBC (IDIBELL), Barcelona, Spain.ORCID 0000-0002-5487-8113
Namrata D UdeshiCancer Program, Broad Institute of Harvard and MIT, Cambridge, Massachusetts.
Lior GolombDepartment of Medical Oncology, Dana Farber Cancer Institute, Boston, Massachusetts.
Zhong WuDepartment of Medical Oncology, Dana Farber Cancer Institute, Boston, Massachusetts.
Jin ZhouDepartment of Medical Oncology, Dana Farber Cancer Institute, Boston, Massachusetts.
Tanya SvinkinaCancer Program, Broad Institute of Harvard and MIT, Cambridge, Massachusetts.
Estrella Aguilera-JimenezDepartment of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah.ORCID 0000-0002-4160-2855
Yanli LiuDepartment of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah.
Steven A CarrCancer Program, Broad Institute of Harvard and MIT, Cambridge, Massachusetts.
Montse Sanchez-CespedesCancer Epigenetics and Biology Program-PEBC (IDIBELL), Barcelona, Spain.
Matthew MeyersonDepartment of Medical Oncology, Dana Farber Cancer Institute, Boston, Massachusetts. Xiaoyang.Zhang@hci.utah.edu Matthew_Meyerson@dfci.harvard.edu.
Xiaoyang ZhangDepartment of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah. Xiaoyang.Zhang@hci.utah.edu Matthew_Meyerson@dfci.harvard.edu.
Broad Institute · USHuntsman Cancer Institute · USInstitut d'Investigació Biomédica de Bellvitge · ES

Funding

NKX2-1 Enhancer Amplification and Lineage Addiction in Lung AdenocarcinomaR35CA197568 · NCI · DANA-FARBER CANCER INST · PI Matthew L. Meyerson · 2015 to 2026
$12.4M
MICROSCALED PROTEOGENOMICS FOR CANCER CLINICAL TRIALSU01CA214125 · NCI · BAYLOR COLLEGE OF MEDICINE · PI ANURAG, MEENAKSHI, CARR, STEVEN A · 2017 to 2021
$7.0M
Center of Excellence for High Throughput Proteogenomic CharacterizationU24CA210986 · NCI · BROAD INSTITUTE, INC. · PI CARR, STEVEN A, GILLETTE, MICHAEL A · 2016 to 2020
$6.4M
NCI NIH HHS R35 CA197568NCI NIH HHS U01 CA214125NCI NIH HHS U24 CA210986
6 · The paper itself

Abstract

Genomic analysis of lung adenocarcinomas has revealed that the

Indexed as

A549 CellsAdenocarcinoma of LungBasic Helix-Loop-Helix Leucine Zipper Transcription FactorsBasic Helix-Loop-Helix ProteinsCell Line, TumorCell ProliferationHEK293 CellsHumansLung NeoplasmsMutationProto-Oncogene Proteins c-mycBasic Helix-Loop-Helix Leucine Zipper Transcription FactorsBasic Helix-Loop-Helix ProteinsMAX protein, humanMGA protein, humanMYC protein, humanProto-Oncogene Proteins c-myc

Identifiers

PMID31862696
PMCPMC7219472
OpenAlexW2994611188

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.