ArticleChest2020
Neighborhood Disadvantage and Lung Cancer Incidence in Ever-Smokers at a Safety Net Health-Care System: A Retrospective Study.
Article in Chest, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.
- Systematic review of neighborhood socioeconomic indices studied across the cancer control continuum.Cancer medicine · 2022Pooled it
- Association of individual and neighborhood socioeconomic status with outcomes of a smoking cessation intervention provided in the lung cancer screening setting.Preventive medicine · 2025Trial
- Neighborhood deprivation and lung cancer incidence and mortality in patients with asthma: a nationwide cohort study in Sweden, 1997-2018.Respiratory research · 2026Article
- Precision greenness exposure is associated with lung cancer risk in medicare beneficiaries.Cancer causes & control : CCC · 2026Article
- The impact of neighbourhood material and social disadvantage on respiratory health across Canada.The European respiratory journal · 2026Article
- Community-level contextual factors associated with lung cancer: a hot spot analysis.Cancer causes & control : CCC · 2026Article
- Article
- Generation of machine-learning derived cancer vulnerability indicator to determine the spatial burden of cancer outcomes.PloS one · 2026Article
- A Geospatial Analysis of the Lung Cancer Burden in Philadelphia, Using Pennsylvania Cancer Registry Data from 2008-2017.International journal of environmental research and public health · 2025Article
- Article
- Social Genomic Determinants of Health: Understanding the Molecular Pathways by Which Neighborhood Disadvantage Affects Cancer Outcomes.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2024Review
- Neighborhood-level deprivation and survival in lung cancer.BMC cancer · 2024Article
- Relative predictive value of sociodemographic factors for chronic diseases among All of Us participants: a descriptive analysis.BMC public health · 2024Article
- Social Determinants of Health Framework to Identify and Reduce Barriers to Imaging in Marginalized Communities.Radiology · 2024Review
- Realizing the potential of social determinants data in EHR systems: A scoping review of approaches for screening, linkage, extraction, analysis, and interventions.Journal of clinical and translational science · 2024Article
- Identifying priority populations for lung cancer screening intervention using neighborhood-level factors and cancer registry data.Preventive oncology & epidemiology · 2024Article
- Racial/Ethnic disparities in exposure to neighborhood violence and lung cancer risk in Chicago.Social science & medicine (1982) · 2024Article
- Article
- Place and Pulmonary Health Inequality.Annals of the American Thoracic Society · 2023Article
- The role of area-level socioeconomic disadvantage in racial disparities in cancer incidence in metropolitan Detroit.Cancer medicine · 2023Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundNeighborhood circumstances have an influence on multiple health outcomes, but the association between neighborhood conditions and lung cancer incidence has not been studied in sufficient detail. The goal of this study was to understand whether neighborhood conditions are independently associated with lung cancer incidence in ever-smokers after adjusting for individual smoking exposure and other risk factors.
methodsA cohort of ever-smokers aged ≥ 55 years was assembled from 19 years of electronic health record data from our academic community health-care system. Patient demographic characteristics and other measures known to be associated with lung cancer were ascertained. Patient addresses at their index visit were geocoded to the census block group level to determine the area deprivation index (ADI), drawn from 5-year estimates from the American Community Survey. A multivariate Cox proportional hazards model was fit to assess the association between ADI and time to lung cancer diagnosis. Tests of statistical significance were two-sided.
resultsThe study included 19,867 male subjects and 21,748 female subjects. Fifty-three percent of the patients were white, 38% were black, and 5% were Hispanic. Of these, 1,149 developed lung cancer. After adjusting for known risk factors, patients residing in the most disadvantaged areas had a significantly increased incidence of lung cancer compared with those in the least disadvantaged areas (hazard ratio, 1.29; 95% CI 1.07-1.55).
conclusionsCensus-derived estimates of neighborhood conditions have a powerful association with lung cancer incidence, even when adjusting for individual variables. Further research investigating the mechanisms that link neighborhood conditions to lung cancer is warranted.
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