Evidence map›Paper›PMID 31862019›Full record

ArticleJournal of the American Association for Laboratory Animal Science : JAALAS2020

Comparing Mouse Health Monitoring Between Soiled-bedding Sentinel and Exhaust Air Dust Surveillance Programs.

Darya Mailhiot, Allison M Ostdiek, Kerith R Luchins, Chago J Bowers, Betty R Theriault, George P Langan

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Association for Laboratory Animal Science : JAALAS, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 2 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Enhancing Rodent Welfare, Cost Savings, and Efficiency: Implementation and Review of Data-Driven Improvements.Journal of the American Association for Laboratory Animal Science : JAALAS · 2026
    Review
  6. Article
  7. The Use of Ampicillin-Medicated Diet to Treat Segmented Filamentous Bacteria in a Mouse (Mus musculus) Colony.Journal of the American Association for Laboratory Animal Science : JAALAS · 2025
    Article
  8. Article
  9. Evaluation of Direct Colony Sampling Compared with Sentinel-Free Soiled Bedding Testing for Murine Quarantine Programs.Journal of the American Association for Laboratory Animal Science : JAALAS · 2025
    Article
  10. Improved Detection of Murine Pathogens Using Sentinel-Free Media Compared to Live Animal Sampling.Journal of the American Association for Laboratory Animal Science : JAALAS · 2025
    Article
  11. Rodent Pathogen Detection via Testing of Soiled Nesting Material.Journal of the American Association for Laboratory Animal Science : JAALAS · 2025
    Article
  12. Detection and Remediation of Pneumocystis murina Infections by Environmental Health Monitoring.Journal of the American Association for Laboratory Animal Science : JAALAS · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Pathogen Prevalence Estimates and Diagnostic Methodology Trends in Laboratory Mice and Rats from 2003 to 2020.Journal of the American Association for Laboratory Animal Science : JAALAS · 2023
    Article
  17. Preference of Escaped Mice for Live Capture or Glue Traps and Relevance to Pest Control Programs.Journal of the American Association for Laboratory Animal Science : JAALAS · 2023
    Article
  18. A Cross-sectional Survey on Rodent Environmental Health Monitoring Practices: Benchmarking, Associations, and Barriers.Journal of the American Association for Laboratory Animal Science : JAALAS · 2023
    Article
  19. Article
  20. Single-tube Multiplex Nested PCR System for Efficient Detection of Pathogenic Microorganisms in SPF Rodents.Journal of the American Association for Laboratory Animal Science : JAALAS · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Darya Mailhiot
Allison M Ostdiek
Kerith R Luchins
Chago J Bowers
Betty R Theriault
George P Langan
Genetic Resources Center · JPUniversity of Chicago · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To monitor rodent colony health in research facilities, soiled-bedding sentinel (SBS) animals have traditionally been used. SBS can be tested by various methods, which may include serology, PCR analysis, and necropsy. Several pathogens are unreliably detected by using SBS or transmitted poorly through soiled bedding, and collection and evaluation of SBS samples can be time-intensive. Recently, exhaust air dust (EAD) testing through PCR analysis has emerged as an adjunct or replacement method for rodent colony health monitoring. EAD monitoring may provide a more efficient, sensitive, and humane method for monitoring health status. Using both EAD and SBS health monitoring, we evaluated colony health over the course of 1 y in 3 research barrier rooms in which mice were housed exclusively on IVC racks. Three pathogens-

Indexed as

Housing, AnimalMiceAnimalsBacterial InfectionsBedding and LinensCaliciviridae InfectionsDustHelicobacterLaboratory Animal ScienceNorovirusPasteurellaceaeRodent DiseasesSentinel SurveillanceDust

Identifiers

PMID31862019
PMCPMC6978580
OpenAlexW2994620170

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.