Evidence map›Paper›PMID 31861860›Full record

ArticleBrain sciences2019

Genetic Screening of Plasticity Regulating Nogo-Type Signaling Genes in Migraine.

Gabriella Smedfors, Franziska Liesecke, Caroline Ran, Lars Olson, Tobias E Karlsson, Andrea Carmine Belin

Open access · goldAbstract read
In one paragraph

Article in Brain sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 78% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Gabriella SmedforsKarolinska Institutet, Department of Neuroscience, Biomedicum, Solnavägen 9, 17177 Stockholm, Sweden.
Franziska LieseckeKarolinska Institutet, Department of Neuroscience, Biomedicum, Solnavägen 9, 17177 Stockholm, Sweden.
Caroline RanKarolinska Institutet, Department of Neuroscience, Biomedicum, Solnavägen 9, 17177 Stockholm, Sweden.ORCID 0000-0003-0239-9871
Lars OlsonKarolinska Institutet, Department of Neuroscience, Biomedicum, Solnavägen 9, 17177 Stockholm, Sweden.
Tobias E KarlssonKarolinska Institutet, Department of Neuroscience, Biomedicum, Solnavägen 9, 17177 Stockholm, Sweden.
Andrea Carmine BelinKarolinska Institutet, Department of Neuroscience, Biomedicum, Solnavägen 9, 17177 Stockholm, Sweden.ORCID 0000-0001-6668-3172
Karolinska Institutet · SE

Funding

A donation by Per Nydahl 2019Karolinska Institute Clinical Scientist Training Programme: CSTP 2013Karolinska Institutet Program for "Forskar AT" 2016Karolinska Institutet Research Funds 2018-01738Magnus Bergvalls Stiftelse 2018-02920The Swedish Brain Foundation FO2018The Swedish Brain Foundation FO2018-0008The Swedish Research Council 2017-01096The Swedish Research Council K2012-62X-03185-42-4
6 · The paper itself

Abstract

Migraine is the sixth most prevalent disease in the world and a substantial number of experiments have been conducted to analyze potential differences between the migraine brain and the healthy brain. Results from these investigations point to the possibility that development and aggravation of migraine may include grey matter plasticity. Nogo-type signaling is a potent plasticity regulating system in the CNS and consists of ligands, receptors, co-receptors and modulators with a dynamic age- and activity-related expression in cortical and subcortical regions. Here we investigated a potential link between migraine and five key Nogo-type signaling genes:

Indexed as

association studygrey matterheadachesignalingSNP

Identifiers

PMID31861860
PMCPMC7016645
OpenAlexW2996305182

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.