Evidence map›Paper›PMID 31861834›Full record

ArticleNanomaterials (Basel, Switzerland)2019

Mechanical Properties and Cytotoxicity of Differently Structured Nanocellulose-hydroxyapatite Based Composites for Bone Regeneration Application.

Vijay H Ingole, Tomaž Vuherer, Uroš Maver, Aruna Vinchurkar, Anil V Ghule, Vanja Kokol

Abstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Avian Egg: A Multifaceted Biomaterial for Tissue Engineering.Industrial & engineering chemistry research · 2021
    Article
  12. Review
  13. Biotechnological Applications of Eggshell: Recent Advances.Frontiers in bioengineering and biotechnology · 2021
    Review
  14. Review
  15. Biomimetic ZnO for Dye-Sensitized Solar Cells.Nanomaterials (Basel, Switzerland) · 2020
    Article
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Vijay H IngoleDepartment of Nanotechnology, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad 431004, Maharashtra, India.
Tomaž VuhererInstitute of Engineering Materials and Design, Faculty of Mechanical Engineering, University of Maribor, Smetanova ulica 17, Maribor SI-2000, Slovenia.
Uroš MaverInstitute of Biomedical Sciences and Department of Pharmacology, Faculty of Medicine, University of Maribor, Taborska ulica 8, Maribor SI-2000, Slovenia.ORCID 0000-0002-2237-3786
Aruna VinchurkarDepartment of Biophysics, Government Institute of Science, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad 431004, Maharashtra, India.
Anil V GhuleDepartment of Nanotechnology, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad 431004, Maharashtra, India.
Vanja KokolInstitute of Engineering Materials and Design, Faculty of Mechanical Engineering, University of Maribor, Smetanova ulica 17, Maribor SI-2000, Slovenia.ORCID 0000-0002-8521-0941

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The nanocomposites were prepared by synthesizing (2,2,6,6-tetramethylpiperidin-1-yl)oxyl (TEMPO)-oxidized cellulose nanofibrils (TCNFs) or cellulose nanocrystals (CNCs) with hydroxyapatite (HA) in varying composition ratios in situ. These nanocomposites were first obtained from eggshell-derived calcium and phosphate of ammonium dihydrogen orthophosphate as precursors at a stoichiometric Ca/P ratio of 1.67 with ultrasonication and compressed further by a uniaxial high-pressure technique. Different spectroscopic, microscopic, and thermogravimetric analyses were used to evaluate their structural, crystalline, and morphological properties, while their mechanical properties were assessed by an indentation method. The contents of TCNF and CNC were shown to render the formation of the HA crystallites and thus influenced strongly on the composite nanostructure and further on the mechanical properties. In this sense, the TCNF-based composites with relatively higher contents (30 and 40 wt %) of semicrystalline and flexible TCNFs resulted in smoother and more uniformly distributed HA particles with good interconnectivity, a hardness range of 550-640 MPa, a compression strength range of 110-180 MPa, an elastic modulus of ~5 GPa, and a fracture toughness value of ~6 MPa

Indexed as

cytotoxicityhydroxyapatitemechanical propertiesnanocellulosenanocomposites

Identifiers

PMID31861834
PMCPMC7022391

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.