Evidence map›Paper›PMID 31861832›Full record

ArticleInternational journal of molecular sciences2019

Detection of Loss of Heterozygosity in cfDNA of Advanced

Elisa Boldrin, Giorgia Nardo, Elisabetta Zulato, Laura Bonanno, Valentina Polo, Stefano Frega, Alberto Pavan, Stefano Indraccolo, Daniela Saggioro

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Properties and Application of Cell-Free DNA as a Clinical Biomarker.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Elisa BoldrinImmunology and Molecular Oncology Unit, Istituto Oncologico Veneto IOV-IRCCS, Via Gattamelata 64, 35128 Padova, Italy.ORCID 0000-0002-7898-5845
Giorgia NardoImmunology and Molecular Oncology Unit, Istituto Oncologico Veneto IOV-IRCCS, Via Gattamelata 64, 35128 Padova, Italy.
Elisabetta ZulatoImmunology and Molecular Oncology Unit, Istituto Oncologico Veneto IOV-IRCCS, Via Gattamelata 64, 35128 Padova, Italy.
Laura BonannoMedical Oncology 2, Istituto Oncologico Veneto IOV-IRCCS, Via Gattamelata 64, 35128 Padova, Italy.ORCID 0000-0002-4810-7136
Valentina PoloMedical Oncology, Azienda ULSS 2, 31100 Treviso, Italy.
Stefano FregaMedical Oncology 2, Istituto Oncologico Veneto IOV-IRCCS, Via Gattamelata 64, 35128 Padova, Italy.
Alberto PavanMedical Oncology 2, Istituto Oncologico Veneto IOV-IRCCS, Via Gattamelata 64, 35128 Padova, Italy.
Stefano IndraccoloImmunology and Molecular Oncology Unit, Istituto Oncologico Veneto IOV-IRCCS, Via Gattamelata 64, 35128 Padova, Italy.
Daniela SaggioroImmunology and Molecular Oncology Unit, Istituto Oncologico Veneto IOV-IRCCS, Via Gattamelata 64, 35128 Padova, Italy.
Istituto Oncologico Veneto · ITAULSS 2 Marca Trevigiana · IT

Funding

IOV Intramural Grant 5x1000undefined <span style="color:gray;font-size:10px;">undefined</span> Intramural Grant 5x1000 IOV
6 · The paper itself

Abstract

Liquid biopsy is currently approved for management of epidermal growth factor receptor (

Indexed as

Loss of HeterozygosityAgedAged, 80 and overCarcinoma, Non-Small-Cell LungCell-Free Nucleic AcidsErbB ReceptorsFemaleHumansLung NeoplasmsMaleMiddle AgedMutationPilot ProjectsProto-Oncogene Proteins p21(ras)Cell-Free Nucleic AcidsEGFR protein, humanErbB ReceptorsKRAS protein, humanProto-Oncogene Proteins p21(ras)cell-free DNA (cfDNA)epidermal growth factor receptor (EGFR)Kirsten rat sarcoma homologous (KRAS)liquid biopsyloss of heterozygosity (LOH)non-small-cell lung cancer (NSCLC)

Identifiers

PMID31861832
PMCPMC6981934
OpenAlexW2996615374

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.