Evidence map›Paper›PMID 31861635›Full record

ArticleCells2019

Multiple Sclerosis CD49d

Paweł Piatek, Magdalena Namiecinska, Małgorzata Domowicz, Marek Wieczorek, Sylwia Michlewska, Mariola Matysiak, Natalia Lewkowicz, Maciej Tarkowski, Przemysław Lewkowicz

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Remyelination in multiple sclerosis from the miRNA perspective.Frontiers in molecular neuroscience · 2023
    Review
  3. Article
  4. Review
  5. Article
  6. MS CD49dCells · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Paweł PiatekDepartment of Neurology, Laboratory of Neuroimmunology, Medical University of Lodz, Poland, ul. Pomorska 251, 92-213 Lodz, Poland.
Magdalena NamiecinskaDepartment of Neurology, Laboratory of Neuroimmunology, Medical University of Lodz, Poland, ul. Pomorska 251, 92-213 Lodz, Poland.
Małgorzata DomowiczDepartment of Neurology, Laboratory of Neuroimmunology, Medical University of Lodz, Poland, ul. Pomorska 251, 92-213 Lodz, Poland.
Marek WieczorekDepartment of Neurobiology, Faculty of Biology and Environmental Protection, University of Lodz, 90-236 Lodz, Poland.
Sylwia MichlewskaLaboratory of Microscopic Imaging and Specialized Biological Techniques, Faculty of Biology and Environmental Protection, University of Lodz, 90-237 Lodz, Poland.
Mariola MatysiakDepartment of Neurology, Laboratory of Neuroimmunology, Medical University of Lodz, Poland, ul. Pomorska 251, 92-213 Lodz, Poland.
Natalia LewkowiczDepartment of General Dentistry, Medical University of Lodz, 92-213 Lodz, Poland.
Maciej TarkowskiDepartment of Biomedical and Clinical Sciences, Luigi Sacco, University Hospital, University of Milan, 20122 Milano, Italy.
Przemysław LewkowiczDepartment of Neurology, Laboratory of Neuroimmunology, Medical University of Lodz, Poland, ul. Pomorska 251, 92-213 Lodz, Poland.
Medical University of Lodz · PLUniversity of Łódź · PLUniversity of Milan · IT

Funding

Narodowe Centrum Nauki 2014/13/B/NZ6/00235
6 · The paper itself

Abstract

Multiple sclerosis (MS) is a demyelinating autoimmune disease of the central nervous system (CNS) mediated by autoreactive lymphocytes. The role of autoreactive lymphocytes in the CNS demyelination is well described, whereas very little is known about their role in remyelination during MS remission. In this study, we identified a new subpopulation of myelin-specific CD49d

Indexed as

AdultAnimalsCase-Control StudiesCD40 LigandCell ProliferationCells, CulturedCoculture TechniquesCytokinesDisease Models, AnimalEncephalomyelitis, Autoimmune, ExperimentalFemaleHumansIntegrin alpha4LymphocytesMaleMiceCD40 LigandCytokinesIntegrin alpha4Myelin-Oligodendrocyte Glycoproteinmyelin oligodendrocyte glycoprotein (35-50), Ala(37)-Peptide Fragmentsmultiple sclerosismyelin-specific lymphocytesremyelination

Identifiers

PMID31861635
PMCPMC7017443
OpenAlexW2994807776

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.