Evidence map›Paper›PMID 31861525›Full record

ArticleMolecules (Basel, Switzerland)2019

Protopine Protects Mice against LPS-Induced Acute Kidney Injury by Inhibiting Apoptosis and Inflammation via the TLR4 Signaling Pathway.

Beibei Zhang, Mengnan Zeng, Meng Li, Yuxuan Kan, Benke Li, Ruiqi Xu, Yuanyuan Wu, Shengchao Wang, Xiaoke Zheng, Weisheng Feng

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 76 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Plants (Basel, Switzerland) · 2025
    Review
  6. Article
  7. Role of miRNAs in macrophage-mediated kidney injury.Pediatric nephrology (Berlin, Germany) · 2024
    Review
  8. Article
  9. Article
  10. Article
  11. Article
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  19. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Beibei ZhangCollege of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450046, China.
Mengnan ZengCollege of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450046, China.
Meng LiCollege of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450046, China.
Yuxuan KanCollege of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450046, China.
Benke LiCollege of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450046, China.
Ruiqi XuCollege of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450046, China.
Yuanyuan WuCollege of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450046, China.
Shengchao WangCollege of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450046, China.
Xiaoke ZhengCollege of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450046, China.
Weisheng FengCollege of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450046, China.
First Affiliated Hospital of Henan University · CN

Funding

Science and Technology Department of Henan Province 171100310500
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Acute Kidney InjuryAnimalsAnti-Inflammatory Agents, Non-SteroidalApoptosisBenzophenanthridinesBerberine AlkaloidsBlood Urea NitrogenCorydalisCreatinineCytokinesDisease Models, AnimalGene Expression RegulationKidneyKidney Function TestsLipopolysaccharidesMiceAnti-Inflammatory Agents, Non-SteroidalBenzophenanthridinesBerberine AlkaloidsCreatinineCytokinesLipopolysaccharidesprotopineTlr4 protein, mouseToll-Like Receptor 4acute kidney injuryapoptosisinflammationprotopineTLR4 signaling pathway

Identifiers

PMID31861525
PMCPMC6982873
OpenAlexW2996098476

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.