Evidence map›Paper›PMID 31861479›Full record

ArticleCancers2019

Polyclonal Immunoglobulin Recovery after Autologous Stem Cell Transplantation Is an Independent Prognostic Factor for Survival Outcome in Patients with Multiple Myeloma.

Shuji Ozaki, Takeshi Harada, Hikaru Yagi, Etsuko Sekimoto, Hironobu Shibata, Toshio Shigekiyo, Shiro Fujii, Shingen Nakamura, Hirokazu Miki, Kumiko Kagawa and 1 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Shuji OzakiDepartment of Hematology, Tokushima Prefectural Central Hospital, Tokushima 770-8539, Japan.
Takeshi HaradaDepartment of Hematology, Tokushima University Hospital, Tokushima 770-8503, Japan.
Hikaru YagiDepartment of Hematology, Tokushima Prefectural Central Hospital, Tokushima 770-8539, Japan.
Etsuko SekimotoDepartment of Hematology, Tokushima Prefectural Central Hospital, Tokushima 770-8539, Japan.
Hironobu ShibataDepartment of Hematology, Tokushima Prefectural Central Hospital, Tokushima 770-8539, Japan.
Toshio ShigekiyoDepartment of Hematology, Tokushima Prefectural Central Hospital, Tokushima 770-8539, Japan.
Shiro FujiiDepartment of Hematology, Tokushima University Hospital, Tokushima 770-8503, Japan.
Shingen NakamuraDepartment of Hematology, Tokushima University Hospital, Tokushima 770-8503, Japan.
Hirokazu MikiDepartment of Hematology, Tokushima University Hospital, Tokushima 770-8503, Japan.
Kumiko KagawaDepartment of Hematology, Tokushima University Hospital, Tokushima 770-8503, Japan.
Masahiro AbeDepartment of Hematology, Tokushima University Hospital, Tokushima 770-8503, Japan.
Tokushima University Hospital · JPTokushima Prefectural Central Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We retrospectively analyzed multiple myeloma (MM) patients who underwent autologous stem cell transplantation (ASCT) without maintenance therapy to assess the impact of recovery of normal immunoglobulin (Ig) on clinical outcomes. The recovery of polyclonal Ig was defined as normalization of all values of serum IgG, IgA, and IgM 1 year after ASCT. Among 50 patients, 26 patients showed polyclonal Ig recovery; 14 patients were in ≥complete response (CR) and 12 remained in non-CR after ASCT. The patients with Ig recovery exhibited a significantly better progression-free survival (PFS, median, 46.8 vs 26.7 months,

Indexed as

autologous stem cell transplantationimmunoglobulin recoverymultiple myeloma

Identifiers

PMID31861479
PMCPMC7016673
OpenAlexW2994719829

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.