Evidence map›Paper›PMID 31861434›Full record

ArticleNutrients2019

Polarization of Macrophages in Human Adipose Tissue is Related to the Fatty Acid Spectrum in Membrane Phospholipids.

Rudolf Poledne, Hana Malinska, Hana Kubatova, Jiri Fronek, Filip Thieme, Sona Kauerova, Ivana Kralova Lesna

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 41 citations in OpenAlex.

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  15. Cholesterol in the Cell Membrane-An Emerging Player in Atherogenesis.International journal of molecular sciences · 2022
    Review
  16. Review
  17. Article
  18. Review
  19. Age and Sex: Impact on adipose tissue metabolism and inflammation.Mechanisms of ageing and development · 2021
    Review
  20. Anti-inflammatory effect of fish oil in human adipose tissue.International journal of obesity (2005) · 2021
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Rudolf PoledneCentre for Experimental Medicine, Institute for Clinical and Experimental Medicine, 140-21 Prague, Czech Republic.
Hana MalinskaCentre for Experimental Medicine, Institute for Clinical and Experimental Medicine, 140-21 Prague, Czech Republic.
Hana KubatovaCentre for Experimental Medicine, Institute for Clinical and Experimental Medicine, 140-21 Prague, Czech Republic.
Jiri FronekTransplant Surgery Dept., Institute for Clinical and Experimental Medicine, 140-21 Prague, Czech Republic.
Filip ThiemeTransplant Surgery Dept., Institute for Clinical and Experimental Medicine, 140-21 Prague, Czech Republic.
Sona KauerovaCentre for Experimental Medicine, Institute for Clinical and Experimental Medicine, 140-21 Prague, Czech Republic.
Ivana Kralova LesnaCentre for Experimental Medicine, Institute for Clinical and Experimental Medicine, 140-21 Prague, Czech Republic.
Institute of Clinical and Experimental Medicine · CZ

Funding

Ministerstvo Zdravotnictví Ceské Republiky 17-28103A
6 · The paper itself

Abstract

Residential macrophages in adipose tissue play a pivotal role in the development of inflammation not only within this tissue, but also affect the proinflammatory status of the whole body. Data on human adipose tissue inflammation and the role of macrophages are rather scarce. We previously documented that the proportion of proinflammatory macrophages in human adipose tissue correlates closely with non-HDL cholesterol concentrations. We hypothesized that this is due to the identical influence of diet on both parameters and decided to analyze the fatty acid spectrum in cell membrane phospholipids of the same individuals as a parameter of the diet consumed. Proinflammatory and anti-inflammatory macrophages were isolated from human adipose tissue (

Indexed as

Adipose TissueAdultCell MembraneDietFatty AcidsFemaleHumansMacrophagesMaleMiddle AgedPhospholipidsFatty AcidsPhospholipidsinflammationmacrophagesmembranenutritionomega-3 fatty acids

Identifiers

PMID31861434
PMCPMC7020093
OpenAlexW2995421646

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.