Evidence map›Paper›PMID 31861403›Full record

ArticleMarine drugs2019

Protective Action of

Manon Le Goff, Antoine Delbrut, Marie Quinton, Rémi Pradelles, Maelle Bescher, Agnès Burel, Benoît Schoefs, Odile Sergent, Dominique Lagadic-Gossmann, Eric Le Ferrec and 1 more

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Foods (Basel, Switzerland) · 2023
    Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Manon Le GoffEA 2160 Mer Molécules Santé-MIMMA, IUML FR-3473 CNRS, Le Mans Université, F-53020 Laval, France.
Antoine DelbrutMicrophyt, 713 Route de Mudaison, 34630 Baillargues, France.
Marie QuintonMicrophyt, 713 Route de Mudaison, 34630 Baillargues, France.
Rémi PradellesMicrophyt, 713 Route de Mudaison, 34630 Baillargues, France.
Maelle BescherUniv Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail)-UMR_S 1085, F-35000 Rennes, France.
Agnès BurelUniv Rennes, Biosit-UMS 3480, US_S 018, F-35000 Rennes, France.
Benoît SchoefsEA 2160 Mer Molécules Santé-MIMMA, IUML FR-3473 CNRS, Le Mans Université, F-53020 Laval, France.
Odile SergentUniv Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail)-UMR_S 1085, F-35000 Rennes, France.
Dominique Lagadic-GossmannUniv Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail)-UMR_S 1085, F-35000 Rennes, France.
Eric Le FerrecUniv Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail)-UMR_S 1085, F-35000 Rennes, France.
Lionel UlmannEA 2160 Mer Molécules Santé-MIMMA, IUML FR-3473 CNRS, Le Mans Université, F-53020 Laval, France.
Inserm · FRCentre National de la Recherche Scientifique · FRStructure Fédérative de Recherche en Biologie et Santé de Rennes · FR

Funding

Cancéropôle Grand-Ouest / Région Bretagne Concerto projectCollectivités Locales Mayennaises Laval AggloITMO Cancer Plan 2014-2019 EST-2016/1/31
6 · The paper itself

Abstract

Marine microalgae are known to be a source of bioactive molecules of interest to human health, such as n-3 polyunsaturated fatty acids (n-3 PUFAs) and carotenoids. The fact that some of these natural compounds are known to exhibit anti-inflammatory, antioxidant, anti-proliferative, and apoptosis-inducing effects, demonstrates their potential use in preventing cancers and cardiovascular diseases (CVDs). Benzo[a]pyrene (B[a]P), a polycyclic aromatic hydrocarbon (PAH), is an ubiquitous environmental pollutant known to contribute to the development or aggravation of human diseases, such as cancer, CVDs, and immune dysfunction. Most of these deleterious effects are related to the activation of the polycyclic aromatic hydrocarbon receptor (AhR). In this context, two ethanolic microalgal extracts with concentrations of 0.1 to 5 µg/mL are tested,

Indexed as

ApoptosisBenzo(a)pyreneBiological ProductsCell LineCell SurvivalCytochrome P-450 CYP1A1CytokinesEndothelial CellsExtracellular VesiclesHumansMicroalgaeOceans and SeasBenzo(a)pyreneBiological ProductsCytochrome P-450 CYP1A1Cytokinesaryl hydrocarbon receptorbenzo[a]pyrenecell protectioncell viabilitycytokinesendothelial cellsextracellular vesiclesmRNA expressionOstreococcus tauriPhaeodactylum tricornutum

Identifiers

PMID31861403
PMCPMC7024323
OpenAlexW2994756189

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.