Evidence map›Paper›PMID 31861380›Full record

ArticleJournal of clinical medicine2019

Machine Learning of Infant Spontaneous Movements for the Early Prediction of Cerebral Palsy: A Multi-Site Cohort Study.

Espen A F Ihlen, Ragnhild Støen, Lynn Boswell, Raye-Ann de Regnier, Toril Fjørtoft, Deborah Gaebler-Spira, Cathrine Labori, Marianne C Loennecken, Michael E Msall, Unn I Möinichen and 7 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 1 pooled it
22.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 1 synthesis or guideline pooled it, 117 citations in OpenAlex.

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  6. An Automated Framework for Pose-Sequence Analysis of Spontaneous Movements in Preterm Infants.IEEE open journal of engineering in medicine and biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 8 institutions in 2 countries.

Espen A F IhlenDepartment of Neuromedicine and Movement Science, Norwegian University of Science and Technology, 7491 Trondheim, Norway.
Ragnhild StøenDepartment of Neonatology, St. Olavs hospital, Trondheim University Hospital, 7006 Trondheim, Norway.
Lynn BoswellAnn and Robert H Lurie Children's Hospital of Chicago, Chicago, IL 60611, USA.
Raye-Ann de RegnierAnn and Robert H Lurie Children's Hospital of Chicago, Chicago, IL 60611, USA.
Toril FjørtoftDepartment of Clinical and Molecular Medicine, Norwegian University of Science and Technology, 7491 Trondheim, Norway.
Deborah Gaebler-SpiraFeinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Cathrine LaboriDepartment of Clinical Therapeutic Services, University Hospital of North Norway, 9038 Tromsø, Norway.
Marianne C LoenneckenDepartment of Pediatrics, Division of Paediatric and Adolescent Medicine, Oslo University Hospital, 0372 Oslo, Norway.
Michael E MsallUniversity of Chicago Medicine, Comer Children's Hospital, Chicago, IL, Section of Developmental and Behavioral Pediatrics, Chicago, IL.60637, USA.
Unn I MöinichenDepartment of Pediatrics, Division of Paediatric and Adolescent Medicine, Oslo University Hospital, 0372 Oslo, Norway.
Colleen PeytonFeinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Michael D SchreiberUniversity of Chicago Medicine, Comer Children's Hospital, Chicago, IL, Section of Developmental and Behavioral Pediatrics, Chicago, IL.60637, USA.
Inger E SilbergDepartment of Pediatrics, Division of Paediatric and Adolescent Medicine, Oslo University Hospital, 0372 Oslo, Norway.
Nils T SongstadDepartment of Pediatrics and Adolescent Medicine, University Hospital of North Norway, 9038 Tromsø, Norway.
Randi T VågenClinic of Clinical Services, St. Olavs hospital, Trondheim University Hospital, 7006 Trondheim, Norway.
Gunn K ØbergDepartment of Clinical Therapeutic Services, University Hospital of North Norway, 9038 Tromsø, Norway.
Lars AddeDepartment of Clinical and Molecular Medicine, Norwegian University of Science and Technology, 7491 Trondheim, Norway.
Norwegian University of Science and Technology · NONorthwestern University · USOslo University Hospital · NOUniversity Hospital of North Norway · NOComer Children's Hospital · USLurie Children's Hospital · USSt Olav's University Hospital · NOUniversity of Chicago · US

Funding

The Liaison Committee between the Central Norway Regional Health Authority and the Norwegian University of Science and Technology, Trondheim, Norway SO: 90056100
6 · The paper itself

Abstract

backgroundEarly identification of cerebral palsy (CP) during infancy will provide opportunities for early therapies and treatments. The aim of the present study was to present a novel machine-learning model, the Computer-based Infant Movement Assessment (CIMA) model, for clinically feasible early CP prediction based on infant video recordings.

methodsThe CIMA model was designed to assess the proportion (%) of CP risk-related movements using a time-frequency decomposition of the movement trajectories of the infant's body parts. The CIMA model was developed and tested on video recordings from a cohort of 377 high-risk infants at 9-15 weeks corrected age to predict CP status and motor function (ambulatory vs. non-ambulatory) at mean 3.7 years age. The performance of the model was compared with results of the general movement assessment (GMA) and neonatal imaging.

resultsThe CIMA model had sensitivity (92.7%) and specificity (81.6%), which was comparable to observational GMA or neonatal cerebral imaging for the prediction of CP. Infants later found to have non-ambulatory CP had significantly more CP risk-related movements (median: 92.8%,

conclusionThe CIMA model may be a clinically feasible alternative to observational GMA.

Indexed as

cerebral palsygeneral movement assessmentmachine learningpremature infants

Identifiers

PMID31861380
PMCPMC7019773
OpenAlexW2996114784

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.