Evidence map›Paper›PMID 31861368›Full record

ReviewMarine drugs2019

Microalgae with Immunomodulatory Activities.

Gennaro Riccio, Chiara Lauritano

Open access · goldAbstract readReview
In one paragraph

Review in Marine drugs, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 176 citations in OpenAlex.

  1. Review
  2. Article
  3. Marine drugs · 2026
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4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Gennaro RiccioDepartment of Marine Biotechnology, Stazione Zoologica Anton Dohrn, CAP80121 Naples, Italy.
Chiara LauritanoDepartment of Marine Biotechnology, Stazione Zoologica Anton Dohrn, CAP80121 Naples, Italy.
Stazione Zoologica Anton Dohrn · IT

Funding

Regione Campania PG/2018/0494374
6 · The paper itself

Abstract

Microalgae are photosynthetic microorganisms adapted to live in very different environments and showing an enormous biochemical and genetic diversity, thus representing an excellent source of new natural products with possible applications in several biotechnological sectors. Microalgae-derived compounds have shown several properties, such as anticancer, antimicrobial, anti-inflammatory, and immunomodulatory. In the last decade, compounds stimulating the immune system, both innate immune response and adaptive immune response, have been used to prevent and fight various pathologies, including cancer (cancer immunotherapy). In this review we report the microalgae that have been shown to possess immunomodulatory properties, the cells and the cellular mediators involved in the mechanisms of action and the experimental models used to test immunostimulatory activities. We also report information on fractions or pure compounds from microalgae identified as having immunostimulatory activity. Given the increasing interest in microalgae as new eco-friendly source of bioactive compounds, we also discuss their possible role as source of new classes of promising drugs to treat human pathologies.

Indexed as

Anti-Bacterial AgentsAnti-Inflammatory AgentsBiological ProductsHumansImmunologic FactorsMicroalgaeOceans and SeasPharmaceutical PreparationsPlant PreparationsAnti-Bacterial AgentsAnti-Inflammatory AgentsBiological ProductsImmunologic FactorsPharmaceutical PreparationsPlant Preparationsimmunomodulatory activitymicroalgaepolyunsaturated fatty acidsulfated polysaccharidessulfolipids

Identifiers

PMID31861368
PMCPMC7024220
OpenAlexW2995940878

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.