Evidence map›Paper›PMID 31861348›Full record

ArticleInternational journal of molecular sciences2019

Insight into

Martina Addeo, Silvia Buonaiuto, Ilaria Guerriero, Elena Amendola, Feliciano Visconte, Antonio Marino, Maria Teresa De Angelis, Filomena Russo, Luca Roberto, Pina Marotta and 6 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Martina AddeoIstituto di Ricerche Genetiche "G. Salvatore", Biogem s.c.ar.l, Ariano Irpino, 83031 Avellino, Italy.
Silvia BuonaiutoDipartimento di Biologia, Università degli Studi di Napoli "Federico II", 80126 Napoli, Italy.
Ilaria GuerrieroIstituto di Ricerche Genetiche "G. Salvatore", Biogem s.c.ar.l, Ariano Irpino, 83031 Avellino, Italy.
Elena AmendolaDipartimento di Biologia, Università degli Studi di Napoli "Federico II", 80126 Napoli, Italy.ORCID 0000-0001-5545-3048
Feliciano VisconteCEINGE Biotecnologie Avanzate s.c.a.r.l., 80131 Napoli, Italy.
Antonio MarinoDipartimento di Biologia, Università degli Studi di Napoli "Federico II", 80126 Napoli, Italy.ORCID 0000-0002-2786-316X
Maria Teresa De AngelisIstituto di Ricerche Genetiche "G. Salvatore", Biogem s.c.ar.l, Ariano Irpino, 83031 Avellino, Italy.
Filomena RussoIstituto di Ricerche Genetiche "G. Salvatore", Biogem s.c.ar.l, Ariano Irpino, 83031 Avellino, Italy.
Luca RobertoIstituto di Ricerche Genetiche "G. Salvatore", Biogem s.c.ar.l, Ariano Irpino, 83031 Avellino, Italy.
Pina MarottaIstituto di Ricerche Genetiche "G. Salvatore", Biogem s.c.ar.l, Ariano Irpino, 83031 Avellino, Italy.ORCID 0000-0001-6857-8325
Nicola Antonino RussoIstituto di Ricerche Genetiche "G. Salvatore", Biogem s.c.ar.l, Ariano Irpino, 83031 Avellino, Italy.
Anna IervolinoIstituto di Ricerche Genetiche "G. Salvatore", Biogem s.c.ar.l, Ariano Irpino, 83031 Avellino, Italy.
Federica AmodioIstituto di Ricerche Genetiche "G. Salvatore", Biogem s.c.ar.l, Ariano Irpino, 83031 Avellino, Italy.
Mario De FeliceIstituto per l'Endocrinologia e l'Oncologia Sperimentale "G. Salvatore", CNR, 80131 Napoli, Italy.
Valeria LucciDipartimento di Biologia, Università degli Studi di Napoli "Federico II", 80126 Napoli, Italy.
Geppino FalcoIstituto di Ricerche Genetiche "G. Salvatore", Biogem s.c.ar.l, Ariano Irpino, 83031 Avellino, Italy.

Funding

Ministero dell'Istruzione, dell'Università e della Ricerca PRIN 2017 XJ38A4Università degli Studi di Napoli Federico II STAR Linea 1
6 · The paper itself

Abstract

Endoderm-derived organs as liver and pancreas are potential targets for regenerative therapies, and thus, there is great interest in understanding the pathways that regulate the induction and specification of this germ layer. Currently, the knowledge of molecular mechanisms that guide the in vivo endoderm specification is restricted by the lack of early endoderm specific markers.

Indexed as

AnimalsBody PatterningCell DifferentiationEmbryonic Stem CellsEndodermGene EditingGene Expression Regulation, DevelopmentalGene TargetingGenetic LociIntercellular Signaling Peptides and ProteinsMiceMice, KnockoutProtein IsoformsIntercellular Signaling Peptides and Proteinsnephrocan protein, mouseProtein Isoforms(CRISPR)/CRISPR-associated systems 9 (Cas9)differentiation, definitive endodermembryonic stem cellsmouse modelNephrocan genetranscriptional variants

Identifiers

PMID31861348
PMCPMC6981620

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.