Evidence map›Paper›PMID 31861298›Full record

ArticleMicromachines2019

A Modular, Reconfigurable Microfabricated Assembly Platform for Microfluidic Transport and Multitype Cell Culture and Drug Testing.

Xin Xie, Sushila Maharjan, Sanwei Liu, Yu Shrike Zhang, Carol Livermore

Open access · goldAbstract read
In one paragraph

Article in Micromachines, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. Modular microfluidics for life sciences.Journal of nanobiotechnology · 2023
    Review
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Xin XieDepartment of Mechanical and Industrial Engineering, Northeastern University, Boston, MA 02115, USA.
Sushila MaharjanDivision of Engineering in Medicine, Brigham and Women's Hospital, Department of Medicine, Harvard Medical School, Cambridge, MA 02139, USA.
Sanwei LiuMEMS Sensors and Actuators Laboratory, Institute for Systems Research, University of Maryland, College Park, MD 20742, USA.
Yu Shrike ZhangDivision of Engineering in Medicine, Brigham and Women's Hospital, Department of Medicine, Harvard Medical School, Cambridge, MA 02139, USA.ORCID 0000-0002-0045-0808
Carol LivermoreDepartment of Mechanical and Industrial Engineering, Northeastern University, Boston, MA 02115, USA.
Brigham and Women's Hospital · USNortheastern University · USSensors (United States) · US

Funding

National Institutes of Health R00CA201603National Institutes of Health R01EB028143National Institutes of Health R21EB025270National Science Foundation Award# 1332249
6 · The paper itself

Abstract

Modular microfluidics offer the opportunity to combine the precise fluid control, rapid sample processing, low sample and reagent volumes, and relatively lower cost of conventional microfluidics with the flexible reconfigurability needed to accommodate the requirements of target applications such as drug toxicity studies. However, combining the capabilities of fully adaptable modular microelectromechanical systems (MEMS) assembly with the simplicity of conventional microfluidic fabrication remains a challenge. A hybrid polydimethylsiloxane (PDMS)-molding/photolithographic process is demonstrated to rapidly fabricate LEGO

Indexed as

cell culturedrug toxicity assaymicrophysiological systemmodular microassemblymodular microfluidics

Identifiers

PMID31861298
PMCPMC7020019
OpenAlexW2996266476

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.