Evidence map›Paper›PMID 31861246›Full record

ArticleGenes2019

Paola Gulías, Jorge Guerra-Varela, Manuela Gonzalez-Aparicio, Ana Ricobaraza, Africa Vales, Gloria Gonzalez-Aseguinolaza, Rubén Hernandez-Alcoceba, Laura Sánchez

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Genetic Manipulation of the Equine Oocyte and Embryo.Journal of equine veterinary science · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Paola GulíasDepartment of Zoology, Genetics and Physical Anthropology, Universidade de Santiago de Compostela, 27002 Lugo, Spain.
Jorge Guerra-VarelaDepartment of Zoology, Genetics and Physical Anthropology, Universidade de Santiago de Compostela, 27002 Lugo, Spain.ORCID 0000-0002-8365-7125
Manuela Gonzalez-AparicioGene Therapy and Regulation of Gene Expression Program, CIMA, FIMA, University of Navarra, Instituto de Investigación Sanitaria de Navarra, IDISNA, Pamplona, 31009 Navarra, Spain.
Ana RicobarazaGene Therapy and Regulation of Gene Expression Program, CIMA, FIMA, University of Navarra, Instituto de Investigación Sanitaria de Navarra, IDISNA, Pamplona, 31009 Navarra, Spain.
Africa ValesGene Therapy and Regulation of Gene Expression Program, CIMA, FIMA, University of Navarra, Instituto de Investigación Sanitaria de Navarra, IDISNA, Pamplona, 31009 Navarra, Spain.
Gloria Gonzalez-AseguinolazaGene Therapy and Regulation of Gene Expression Program, CIMA, FIMA, University of Navarra, Instituto de Investigación Sanitaria de Navarra, IDISNA, Pamplona, 31009 Navarra, Spain.ORCID 0000-0002-1600-4562
Rubén Hernandez-AlcocebaGene Therapy and Regulation of Gene Expression Program, CIMA, FIMA, University of Navarra, Instituto de Investigación Sanitaria de Navarra, IDISNA, Pamplona, 31009 Navarra, Spain.
Laura SánchezDepartment of Zoology, Genetics and Physical Anthropology, Universidade de Santiago de Compostela, 27002 Lugo, Spain.
Navarre Institute of Health Research · ESUniversidade de Santiago de Compostela · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Viral vector use is wide-spread in the field of gene therapy, with new clinical trials starting every year for different human pathologies and a growing number of agents being approved by regulatory agencies. However, preclinical testing is long and expensive, especially during the early stages of development. Nowadays, the model organism par excellence is the mouse (

Indexed as

AdenoviridaeAnimalsBrainEmbryo, NonmammalianGenetic VectorsGreen Fluorescent ProteinsMicroscopy, FluorescenceModels, AnimalZebrafishGreen Fluorescent ProteinsadenovirusDanio reriodelivery systemgene therapyhelper-dependent adenovirushigh-capacity adenoviral vector

Identifiers

PMID31861246
PMCPMC6947401
OpenAlexW2996350930

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.