Evidence map›Paper›PMID 31860950›Full record

ReviewMedicine2019

Management of an extensive odontogenic keratocyst: A rare case report with 10-year follow-up.

Abdul Ahad Khan, Saad Al Qahtani, Ali Azhar Dawasaz, Shahabe A Saquib, Shaik Mohammed Asif, Mohammad Ishfaq, Mohammad Zahir Kota, Mohammed Ibrahim

Open access · goldAbstract readCase ReportsReview
In one paragraph

Review in Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Abdul Ahad KhanDepartment of Oral and Maxillofacial Surgery, College of Dentistry.
Saad Al QahtaniDepartment of Periodontics and Community Dentistry.
Ali Azhar DawasazDepartment of Diagnostic Sciences and Oral Biology.
Shahabe A SaquibDepartment of Periodontics and Community Dentistry.
Shaik Mohammed AsifDepartment of Periodontics and Community Dentistry.
Mohammad IshfaqDepartment of Oral and Maxillofacial Surgery, College of Dentistry, King Khalid University, Abha, Saudi Arabia.
Mohammad Zahir KotaDepartment of Oral and Maxillofacial Surgery, College of Dentistry.
Mohammed IbrahimDepartment of Oral and Maxillofacial Surgery, College of Dentistry.
National Medical Research Center of Dentistry and Maxillofacial Surgery · RUKing Khalid University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe odontogenic keratocyst (OKC), previously known as keratocystic odontogenic tumor has been the most disputable pathologies of the maxillofacial region. Patients with OKC are often asymptomatic but may present with pain, swelling, or discharge. Despite the aggressive nature, previous literature as early as 1970s reported the fact that parakeratinized OKC can be treated by means of marsupialization alone. PATIENTS CONCERNS: The patient had reported with a complaint of pain and swelling in relation with a tooth in mandibular right quadrant. DIAGNOSIS: This case report discusses features of a rare, extensive, panmandibular OKC that is only second of its kind mentioned in the literature.

interventionAs a usual treatment protocol, marsupialization was attempted first. Immunohistochemical analysis revealed reduced expression of Ki-67 and B cell lymphoma 2 (bcl-2) markers after marsupialization from 2 separate sites. However, due to incomplete resolution in the lower right anterior region, an aggressive approach was taken by curetting it out surgically along with associated teeth and cortical plate followed by application of Carnoy's solution. OUTCOME: Postsurgery uneventful healing of the lesion was noted on regular follow-up visits with complete resolution at 40 months. The case has been followed for 10 years with no sign of relapse and reoccurrence.

conclusionsBased on the expression of markers it can thus be concluded that Ki-67 and bcl-2 are site specific and bear strong relationship with the recurrence of OKCs.

Indexed as

AdultBiopsy, NeedleDentistry, OperativeFemaleFollow-Up StudiesHumansImmunohistochemistryMandibular DiseasesOdontogenic CystsPreoperative CareRadiography, DentalRare DiseasesRisk AssessmentSeverity of Illness IndexTime FactorsTreatment Outcome

Identifiers

PMID31860950
PMCPMC6940056
OpenAlexW2995104171

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.