ArticlePloS one2019
Mood and behavioral problems are important predictors of quality of life of nursing home residents with moderate to severe dementia: A cross-sectional study.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 43 citations in OpenAlex.
- Effects of a time-use intervention in isolated patients with coronavirus disease 2019: A randomized controlled study.PloS one · 2023Trial
- Patterns of Daily Administration of Psychoactive Drug Classes for Distress Behavior in Dementia.Journal of the American Medical Directors Association · 2026Article
- Home-Based Occupational Therapy Intervention for the Improvement of Quality of Life in Individuals With Moderate to Severe Dementia and Their Caregivers.Dementia and neurocognitive disorders · 2025Article
- Effects of a Digital, Person-Centered, Photo-Activity Intervention on the Social Interaction of Nursing Home Residents with Dementia, Their Informal Carers and Formal Carers: An Explorative Randomized Controlled Trial.Behavioral sciences (Basel, Switzerland) · 2025Article
- Quality of life and associated characteristics in long-term care residents with advanced dementia in Macao: a cross-sectional study.BMC geriatrics · 2024Article
- Organizational characteristics of highly specialized units for people with dementia and severe challenging behavior.BMC geriatrics · 2024Article
- Clinical profile of trazodone users in a multisetting older population: data from the Italian GeroCovid Observational study.European geriatric medicine · 2023Observational
- The External Validation of the Nursing Homes Short Depression Inventory in Older Adults with Major Neurocognitive Disorders in Long-Term Care Centers.Dementia and geriatric cognitive disorders · 2023Article
- How the Cognitive Status of Older People Affects Their Care Dependency Level and Needs: A Cross-Sectional Study.International journal of environmental research and public health · 2022Article
- Trajectories and determinants of emergency department use among nursing home residents: a time series analysis (2012-2019).BMC geriatrics · 2022Article
- Relationship between the severity of agitation and quality of life in residents with dementia living in German nursing homes - a secondary data analysis.BMC psychiatry · 2021Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo examine the predictors associated with quality of life of nursing home residents with dementia, in order to identify which predictors are most important and hold most promise for future intervention studies. METHODS/
designThis cross-sectional analysis of data collected in two intervention trials included 143 participants with moderate to severe dementia who resided in 40 psychogeriatric wards in 13 nursing homes. The outcome measure quality of life was assessed with the Qualidem. Predictors examined were demographic factors, cognition, mood, behavioral problems, and comorbid conditions.
resultsLinear mixed regression analyses showed that all nine domains of quality of life showed independent (negative) associations with either depression, agitation, apathy, or a combination of these predictors. Agitation, apathy, depression, and the presence of neurological disease explained 50% of the variance in total quality of life. Male gender, psychiatric/mood disorders, and having one or more comorbid conditions was associated with worse social relations, while the presence of comorbid neurological diseases was associated with more social isolation and a worse care relationship. The presence of endocrine/metabolic disorders and pulmonary disorders was associated with less restless tense behavior.
conclusionsDifferent domains of quality of life showed different associations, confirming the multidimensionality of quality of life in nursing home residents with dementia. Quality of life is independently associated with mood and behavioral problems, comorbid conditions, and gender. This knowledge may help to identify older persons at risk of a lower quality of life, and to offer targeted interventions to improve quality of life.
trial registrationDutch Trial registration NTR5641.
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