ArticleeLife2019
Pathway-, layer- and cell-type-specific thalamic input to mouse barrel cortex.
Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
63 citing papers in PubMed, 140 citations in OpenAlex.
- Hyperactivation of distinct thalamic nuclei differentially impairs sleep physiology in rats.Molecular psychiatry · 2026Article
- A human-specific genetic modifier reconfigures large-scale cortical network dynamics underlying behavioral performance.bioRxiv : the preprint server for biology · 2026Article
- 'Backpropagation and the brain' realized in cortical error neuron microcircuits.PLoS computational biology · 2026Article
- Article
- Modeling and simulation of neocortical micro- and mesocircuitry (Part II, Physiology and experimentation).eLife · 2026Article
- Transient synaptic refinement and glial adaptations after whisker denervation in adult mice.Frontiers in cellular neuroscience · 2026Article
- Inhibitory circuit motifs of cortical somatosensory layer 5 SST interneurons are uniform within layers but specific across layers.The Journal of physiology · 2026Article
- Cerebellar climbing fibers impact experience-dependent plasticity in the mouse primary somatosensory cortex.eLife · 2025Article
- Pathway-Specific Ultrastructure of Thalamocortical Synapses in Mouse Somatosensory Area S2.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Computational modeling reveals biological mechanisms underlying the whisker flick EEG.iScience · 2025Article
- Cerebellar climbing fibers impact experience-dependent plasticity in the mouse primary somatosensory cortex.bioRxiv : the preprint server for biology · 2025Article
- Layer 6 Corticothalamic Neurons Induce High Gamma Oscillations Through Cortico-cortical and Cortico-thalamo-cortical Pathways.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Article
- Conditional learning increases inhibition of layer 4 excitatory neurons by somatostatin- and parvalbumin-expressing interneurons in the barrel cortex.Journal of neural transmission (Vienna, Austria : 1996) · 2025Article
- Experience-Dependent Intrinsic Plasticity in Layer IV of Barrel Cortex at Whisking Onset.eNeuro · 2025Article
- Thalamocortical feedback selectively controls pyramidal neuron excitability.Nature communications · 2025Article
- Functional thalamocortical innervation of VIP- and SST-expressing GABAergic interneurons in mouse barrel cortex.iScience · 2025Article
- Cortical dynamics in hand/forelimb S1 and M1 evoked by brief photostimulation of the mouse's hand.eLife · 2025Article
- Molecular states underlying neuronal cell type development and plasticity in the postnatal whisker cortex.PLoS biology · 2025Article
- Immediately following the onset of active whisking, the input layer of barrel cortex exhibits a transient period of increased excitability that depends on prior experience.bioRxiv : the preprint server for biology · 2025Article
3 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 4 countries.
Funding
Abstract
Mouse primary somatosensory barrel cortex (wS1) processes whisker sensory information, receiving input from two distinct thalamic nuclei. The first-order ventral posterior medial (VPM) somatosensory thalamic nucleus most densely innervates layer 4 (L4) barrels, whereas the higher-order posterior thalamic nucleus (medial part, POm) most densely innervates L1 and L5A. We optogenetically stimulated VPM or POm axons, and recorded evoked excitatory postsynaptic potentials (EPSPs) in different cell-types across cortical layers in wS1. We found that excitatory neurons and parvalbumin-expressing inhibitory neurons received the largest EPSPs, dominated by VPM input to L4 and POm input to L5A. In contrast, somatostatin-expressing inhibitory neurons received very little input from either pathway in any layer. Vasoactive intestinal peptide-expressing inhibitory neurons received an intermediate level of excitatory input with less apparent layer-specificity. Our data help understand how wS1 neocortical microcircuits might process and integrate sensory and higher-order inputs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.