ArticlePublic health nutrition2020
Excessive gestational weight gain in the first trimester is associated with risk of gestational diabetes mellitus: a prospective study from Southwest China.
Article in Public health nutrition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- Double Burden of Malnutrition Prevalence in Pregnant Women: Systematic Review and Meta-Analysis.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2026Pooled it
- [A randomized controlled trial of weight management based on mobile health techno-logy among overweight or obese pregnant women].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2025Trial
- Effect of individualized medical nutrition guidance on pregnancy outcomes in older pregnant women.The Journal of international medical research · 2021Trial
- Dose-response relationship between early pregnancy blood pressure and gestational diabetes mellitus based on propensity score matching: a retrospective study.BMC pregnancy and childbirth · 2026Article
- Risk factors for preterm birth in advanced maternal age pregnancies: a retrospective study.BMC pregnancy and childbirth · 2026Review
- What is known about gestational weight gain in Chinese twin pregnancies? A scoping review.BMC pregnancy and childbirth · 2026Article
- Trimester-specific gestational weight gain and adverse outcomes in GDM women: a retrospective cohort study.Frontiers in endocrinology · 2026Article
- Longitudinal Trajectory of Free Fatty Acids in Pregnancy According to First-Trimester Maternal Metabolic Status and the Presence of Gestational Diabetes.Metabolites · 2025Article
- Establishment of a risk prediction model for large-for-gestational-age infants among Chinese women with gestational diabetes mellitus.Scientific reports · 2025Article
- Methods for modeling gestational weight gain: empirical application using electronic health record data from a safety net population.BMC pregnancy and childbirth · 2025Article
- The impact of weight loss in early pregnancy on the incidence of late gestational diabetes: a retrospective cohort study.Frontiers in nutrition · 2025Article
- Article
- Risk factors of late-onset gestational diabetes diagnosed during 24-28 weeks of gestation after normal early screening: a case-control study.Diabetology international · 2024Article
- Investigation of optimal gestational weight gain for twin pregnancy in Southwest China: a retrospective study.Scientific reports · 2023Article
- Insufficient weight management in pregnant women with gestational diabetes mellitus.Osong public health and research perspectives · 2022Article
- Associations of Gestational Diabetes Mellitus and Excessive Gestational Weight Gain with Offspring Obesity Risk.Current medical science · 2022Article
- Gestational Diabetes Mellitus as an Effect Modifier of the Association of Gestational Weight Gain with Perinatal Outcomes: A Prospective Cohort Study in China.International journal of environmental research and public health · 2022Article
- Examining the effects of second-and third-trimester gestational weight gain rates on the perinatal outcomes among Chinese twin pregnancies: a retrospective cohort study.BMC pregnancy and childbirth · 2022Article
- Efficacy of dietary supplements targeting gut microbiota in the prevention and treatment of gestational diabetes mellitus.Frontiers in microbiology · 2022Review
- Gestational Diabetes Mellitus and Energy-Dense Diet: What Is the Role of the Insulin/IGF Axis?Frontiers in endocrinology · 2022Review
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the effects of gestational weight gain (GWG) in the first trimester (GWG-F) and the rate of gestational weight gain in the second trimester (RGWG-S) on gestational diabetes mellitus (GDM), exploring the optimal GWG ranges for the avoidance of GDM in Chinese women.
designA population-based prospective study was conducted. Gestational weight was measured regularly in every antenatal visit and assessed by the Institute of Medicine (IOM) criteria (2009). GDM was assessed with the 75-g, 2-h oral glucose tolerance test at 24-28 weeks of gestation. Multivariable logistic regression was performed to assess the effects of GWG-F and RGWG-S on GDM, stratified by pre-pregnancy BMI. In each BMI category, the GWG values corresponding to the lowest prevalence of GDM were defined as the optimal GWG range.
settingSouthwest China.
participantsPregnant women (n 1910) in 2017.
resultsAfter adjusting for confounders, GWG-F above IOM recommendations increased the risk of GDM (OR; 95 % CI) among underweight (2·500; 1·106, 5·655), normal-weight (1·396; 1·023, 1·906) and overweight/obese women (3·017; 1·118, 8·138) compared with women within IOM recommendations. No significant difference was observed between RGWG-S and GDM (P > 0·05) after adjusting for GWG-F based on the previous model. The optimal GWG-F ranges for the avoidance of GDM were 0·8-1·2, 0·8-1·2 and 0·35-0·70 kg for underweight, normal-weight and overweight/obese women, respectively.
conclusionsExcessive GWG in the first trimester, rather than the second trimester, is associated with increased risk of GDM regardless of pre-pregnancy BMI. Obstetricians should provide more pre-emptive guidance in achieving adequate GWG-F.
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