SynthesisAnnals of the Royal College of Surgeons of England2020
A systematic review and meta-analysis of baseline risk factors for the development of postoperative ileus in patients undergoing gastrointestinal surgery.
Synthesis in Annals of the Royal College of Surgeons of England, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06752317 (Effect of Preoperative Intrathecal Dexamethasone Versus Dexmedetomidine on Paralytic Ileus After Major Abdominal Surgery), which is not on this map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Preoperative Intrathecal Dexamethasone Versus Dexmedetomidine on Paralytic Ileus After Major Abdominal Surgery
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- The Effects of Gum Chewing in the Postoperative-Period: A Systematic Review and Meta-Analysis.ANZ journal of surgeryPooled it
- External validation of predictive models for prolonged postoperative ileus following colorectal resection.International journal of colorectal disease · 2026Article
- Is nasogastric intubation still necessary after pancreaticoduodenectomy? A case-control cohort study.Annals of hepato-biliary-pancreatic surgery · 2026Article
- Irritable bowel syndrome and its impact on utilization and outcomes in elective thoracolumbar fusion.Brain & spine · 2026Article
- Prolonged Postoperative Ileus Following Elective Colectomy: A 2014-2019 National Surgical Quality Improvement Program Analysis.Hawai'i journal of health & social welfare · 2025Article
- Study on the neuroimmune regulatory mechanism of electroacupuncture at Zusanli acupoint for postoperative intestinal paralysis after gastrointestinal surgery.World journal of gastrointestinal surgery · 2025Article
- Postoperative ileus and associated factors in patients following major abdominal surgery in Ethiopia: a prospective cohort study.BMC surgery · 2025Article
- Predicting prolonged postoperative ileus in gastric cancer patients based on bowel sounds using intelligent auscultation and machine learning.World journal of gastrointestinal surgery · 2024Article
- Radical Oophorectomy for Advanced Ovarian Cancer: A Feasibility Study from Tertiary Care Cancer Centre in Eastern India.Journal of obstetrics and gynaecology of India · 2024Article
- Incidence and Risk Factors for Postoperative Ileus after Posterior Surgery in Adolescent Idiopathic Scoliosis.Orthopaedic surgery · 2023Article
- Review
- Postoperative paralytic ileus following debulking surgery in ovarian cancer patients.Frontiers in surgery · 2022Article
- Article
- Postoperative Ileus with the Topical Application of Tongfu Decoction Based on Network Pharmacology and Experimental Validation.Evidence-based complementary and alternative medicine : eCAM · 2022Article
- Risk factors and outcomes associated with postoperative ileus following ileostomy formation: a retrospective study.Perioperative medicine (London, England) · 2021Article
- State-of-the-art colorectal disease: postoperative ileus.International journal of colorectal disease · 2021Review
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionPostoperative ileus occurs frequently following abdominal surgery. Identification of groups at high risk of developing ileus before surgery may allow targeted interventions. This review aimed to identify baseline risk factors for ileus.
methodsA systematic review was conducted with reference to PRISMA and MOOSE guidelines. It was registered on PROSPERO (CRD42017068697). Searches of MEDLINE, EMBASE and CENTRAL were undertaken. Studies reporting baseline risk factors for the development of postoperative ileus based on cohort or trial data and published in English were eligible for inclusion. Dual screening of abstracts and full texts was undertaken. Independent dual extraction was performed. Bias assessment was undertaken using the quality in prognostic studies tool. Meta-analysis using a random effects model was undertaken where two or more studies assessed the same variable.
findingsSearches identified 2,430 papers, of which 28 were included in qualitative analysis and 12 in quantitative analysis. Definitions and incidence of ileus varied between studies. No consistent significant effect was found for association between prior abdominal surgery, age, body mass index, medical comorbidities or smoking status. Male sex was associated with ileus on meta-analysis (odds ratio 1.12, 95% confidence interval 1.02-1.23), although this may reflect unmeasured factors. The literature shows inconsistent effects of baseline factors on the development of postoperative ileus. A large cohort study using consistent definitions of ileus and factors should be undertaken.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.