ArticleMedical & biological engineering & computing2020
Proposal of hemodynamically improved design of an axial flow blood pump for LVAD.
Article in Medical & biological engineering & computing, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 24 citations in OpenAlex.
- Hemodynamic performance and blood damage of the Intra-aortic pumps: A CFD-Based investigation.Medical & biological engineering & computing · 2026Article
- Article
- Analysis of fluid forces impacting on the impeller of a mixed flow blood pump with computational fluid dynamics.The International journal of artificial organs · 2024Article
- Machine learning based on computational fluid dynamics enables geometric design optimisation of the NeoVAD blades.Scientific reports · 2023Article
- Effect of left ventricular assist device on the hemodynamics of a patient-specific left heart.Medical & biological engineering & computing · 2022Article
- Hemolytic Performance in Two Generations of the Sputnik Left Ventricular Assist Device: A Combined Numerical and Experimental Study.Journal of functional biomaterials · 2022Article
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Left ventricular assist devices (LVAD) emerges as an effective clinical device providing life-saving support to heart patients. The design of blood pump of an LVAD involves incredible accuracy and thorough understanding of hemodynamics to mimic the functionality of a healthy ventricle. This work studies hemodynamics around an LVAD and proposes an improved model of axial blood pump for cardiac circulation without any hemolysis complications through numerical investigations. A three-dimensional study on different versions of the impeller with three curved blades (pump I) and spiral blade (pump II) is carried out by utilizing computational fluid dynamics software ANSYS-CFX at a range of rotational speeds and flow rates. The non-Newtonian blood flow through pump is modeled by using Bird-Carreau model. To capture the change in the flow field near the rotating blade, a transient blade row model was employed. The proposal of spiral blade impeller was found to be more compatible as per the hemolytic performance. It considerably reduces the blood damage to two times lesser value than that by pump I and also improves the quality blood flow field. The spiral blade provides a guiding path to the blood particle and avoids mixing of different bloodstreams, thus reducing the eddy losses. Graphical abstract The graphical abstract shows the performance enhancement of the axial blood pump. The model proposed by Peng et al. (Comput Methods Biomech Biomed Engin 17(7):723-727, 2014) has been upgraded to two new versions by redesigning its impeller. Proposed design (pump II) shows improvement in pressure distribution (a) and reduction in hemolysis (in the case of pump II) index (b).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.