Evidence map›Paper›PMID 31858329›Full record

ReviewNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2020

An "all-wheel drive" proposal to accelerate clinical research in common and rare neurological diseases.

Marco Salvetti, Mario A Battaglia, Massimiliano Di Filippo, Gian Luigi Mancardi, Michelangelo Mancuso, Francesco Patti, Maria Pia Sormani, Paola Zaratin

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Marco SalvettiDepartment of Neuroscience Mental Health and Sensory Organs (NEMOS), Sapienza University, Sant' Andrea Hospital, Rome, Italy. marco.salvetti@uniroma1.it.ORCID http://orcid.org/0000-0002-0501-8803
Mario A BattagliaItalian Multiple Sclerosis Foundation, Genoa, Italy.
Massimiliano Di FilippoSection of Neurology, Department of Medicine, Santa Maria Della Misericordia Hospital, University of Perugia, 06132, Perugia, Italy.
Gian Luigi MancardiDepartment of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova and Scientific Clinical Institutes Maugeri IRCCS, Pavia-Genova Nervi, Italy.
Michelangelo MancusoDepartment of Clinical and Experimental Medicine, Neurological Institute, University of Pisa, Pisa, Italy.
Francesco PattiDepartment of Medical and Surgical Sciences, and Advanced Technologies, "G.F. Ingrassia", Multiple Sclerosis Center, University of Catania, Catania, Italy.
Maria Pia SormaniDepartment of Health Sciences, University of Genoa, Genoa, Italy.
Paola ZaratinItalian Multiple Sclerosis Foundation, Genoa, Italy. paola.zaratin@aism.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The complex biology of neurological diseases calls for collaborative efforts that may increase the success rate of clinical research. Models have been proposed, but concrete actions remain insufficient. Based on recent considerations from basic science, from science of patient input and from an analysis of scientific resources in Italy, we here explain why our country may represent an appropriate environment for such actions. Furthermore, we sketch operational framework and business model to be applied in order to accelerate, in parallel, the development of therapies in common and rare diseases.

Indexed as

Biomedical ResearchIntersectoral CollaborationHumansNervous System DiseasesClinical researchMultiple sclerosisPathophysiologyRare diseasesTherapies

Identifiers

PMID31858329
PMCPMC7160195

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.