Evidence map›Paper›PMID 31858232›Full record

Observational studyArchives of dermatological research2020

Invariant natural killer T cells are reduced in peripheral blood of bullous pemphigoid patients and accumulate in lesional skin.

Linda M Mathias, Miriam Harff, Valerie Orth, Silke C Hofmann

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Archives of dermatological research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Linda M Mathias *Department of Dermatology, Allergology and Dermatosurgery, HELIOS University Hospital Wuppertal, University Witten/Herdecke, Heusnerstr. 40, 42283, Wuppertal, Germany.
Miriam Harff *Department of Dermatology, Allergology and Dermatosurgery, HELIOS University Hospital Wuppertal, University Witten/Herdecke, Heusnerstr. 40, 42283, Wuppertal, Germany.
Valerie OrthDepartment of Surgery, HELIOS University Hospital Wuppertal, University Witten/Herdecke, Wuppertal, Germany.
Silke C HofmannDepartment of Dermatology, Allergology and Dermatosurgery, HELIOS University Hospital Wuppertal, University Witten/Herdecke, Heusnerstr. 40, 42283, Wuppertal, Germany. silke.hofmann@helios-gesundheit.de.ORCID http://orcid.org/0000-0002-4221-386X
Helios Universitätsklinikum Wuppertal · DE

Funding

HELIOS Kliniken HELIOS Research Support, ID 002342
6 · The paper itself

Abstract

iNKT (invariant natural killer T) cells are unconventional immunoregulatory T cells which contribute to B cell maturation, antibody and cytokine production. iNKT cells are implicated in the control of autoimmune inflammation in different disorders. For bullous pemphigoid (BP), the most frequent bullous autoimmune dermatosis, the role of iNKT cells has not yet been studied. We, therefore, aimed at investigating the frequency of iNKT cells in peripheral blood and biopsies from lesional and non-lesional skin from patients with BP and controls. Circulating CD3

Indexed as

AdultAgedAged, 80 and overBiopsyCase-Control StudiesFemaleFlow CytometryHealthy VolunteersHumansLymphocyte CountMaleMiddle AgedNatural Killer T-CellsPemphigoid, BullousProspective StudiesSkinAutoantibodyFlow cytometryHemidesmosomeImmunofluorescenceInvariant natural killer T cells

Identifiers

PMID31858232
OpenAlexW2995368247

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.