Evidence map›Paper›PMID 31857910›Full record

ArticlePharmacology research & perspectives2019

Evaluating the centralized purchasing policy for the treatment of hepatitis C: The Colombian CASE.

Angela V Pérez, Antonio J Trujillo, Aurelio E Mejia, Johnny D Contreras, Joshua M Sharfstein

Abstract read
In one paragraph

Article in Pharmacology research & perspectives, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Review
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  5. Article
  6. Aspects that facilitate access to care for viral hepatitis: An evaluative research.Sao Paulo medical journal = Revista paulista de medicina · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Angela V PérezJohns Hopkins Bloomberg School of Public Health 101 North Wolfe Street Apt 415 Baltimore MD USA.ORCID 0000-0001-6272-0626
Antonio J TrujilloInternational Health Johns Hopkins Bloomberg School of Public Health Baltimore MD USA.
Aurelio E MejiaHealth Technologies Ministry of Health and Social Protection Bogotá Colombia.
Johnny D ContrerasMinistry of Health and Social Protection Bogotá Colombia.
Joshua M SharfsteinJohns Hopkins Bloomberg School of Public Health Baltimore MD USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The high cost of drugs for hepatitis C limits access and adherence to treatment. In 2017, the Colombian health care system decided to design a strategy. It consisted of centralized purchasing, regulations, clinical practice guidelines, and direct observation of the treatment and follow-up of patients. The main objective of this study was to assess the centralized purchasing strategy in Colombia. The study design was a policy implementation assessment. We analyzed the change in prices, the clinical outcomes, and the opinions of stakeholders using data from the Ministry of Health. Additional information about effectiveness came from the Colombian Fund for High-Cost Diseases and semi-structured interviews of the stakeholders. The follow-up was from October, 2017 to October, 2018. The total number of patients reported in the cohort period was 1069. The number that finished 12 weeks of treatment, completed the follow-up for the case closure, and were considered cured through the end of October, 2018 was 563 (53%). The remainder, 506 patients (47%), are currently in treatment. A total of 543 of these treated patients (96%) were cured. After implementing this strategy, the drug prices decreased by more than 90% overall. Before implementation, the total direct cost was $100 102 171.75 dollars. Afterward, the cost was $8 378 747 dollars.

Indexed as

Health Plan ImplementationAntiviral AgentsColombiaCost-Benefit AnalysisCost SavingsDelivery of Health CareDrug CostsDrug IndustryFemaleGroup PurchasingHepacivirusHepatitis CHumansMaleMiddle AgedNegotiatingAntiviral AgentsDeveloping countriesHealth policyHigh‐cost drugsPharmacoepidemiologyPolicy designPricing policyRegulatory guidelineStrategic purchasing

Identifiers

PMID31857910
PMCPMC6902741

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.