Evidence map›Paper›PMID 31857899›Full record

ReviewEvolution, medicine, and public health2019

A restoration ecology perspective on the treatment of inflammatory bowel disease.

Matthew R Orr, Kathryn M Kocurek, Yong J Bakos, Ryder C McDowell

Open access · goldAbstract readReview
In one paragraph

Review in Evolution, medicine, and public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Matthew R OrrDepartment of Biology, OSU-Cascades, 1500 SW Chandler Avenue, Bend, OR 97702, USA.ORCID 0000-0002-2546-8625
Kathryn M KocurekFall Creek Internal Medicine, 2160 NE Williamson Court, Bend, OR 97701, USA.
Yong J BakosDepartment of Computer Science, OSU-Cascades, 1500 SW Chandler Avenue, Bend, OR 97702, USA.
Ryder C McDowellDepartment of Computer Science, OSU-Cascades, 1500 SW Chandler Avenue, Bend, OR 97702, USA.
Oregon State University Cascades · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The human gut can be considered an ecosystem comprised of a community of microbes and nonliving components such as food metabolites and food additives. Chronic diseases are increasingly associated with disruption of this ecosystem. The science of restoration ecology was developed to restore degraded ecosystems, but its principles have not been applied widely to gut medicine, including the treatment of inflammatory bowel disease (IBD). One principle of ecological restoration is that 'passive' restoration, which involves removing an ecosystem disturbance, should occur before attempting additional 'active' interventions. We discuss evidence that poor diet is principle source of disturbance in IBD, and therefore requires better attention in its research and clinical care. Another restoration principle is that higher biodiversity may improve ecosystem behavior, but this idea has not been tested for its possible importance in donor stool during fecal microbiota transplants.

Indexed as

dietdysbiosisecological restorationecosystemgutmicrobiome

Identifiers

PMID31857899
PMCPMC6915232
OpenAlexW2991231164

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.