Evidence map›Paper›PMID 31857699›Full record

ArticleLaboratory investigation; a journal of technical methods and pathology2020

Development of multiple features of antigen-induced asthma pathology in a new strain of mast cell deficient BALB/c-Kit

Joseph D Hernandez, Mang Yu, Riccardo Sibilano, Mindy Tsai, Stephen J Galli

Abstract read
In one paragraph

Article in Laboratory investigation; a journal of technical methods and pathology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Joseph D HernandezDepartment of Pathology and the Sean N. Parker Center for Allergy & Asthma Research, Stanford University School of Medicine, Stanford, CA, USA.
Mang YuDepartment of Pathology and the Sean N. Parker Center for Allergy & Asthma Research, Stanford University School of Medicine, Stanford, CA, USA.
Riccardo SibilanoDepartment of Pathology and the Sean N. Parker Center for Allergy & Asthma Research, Stanford University School of Medicine, Stanford, CA, USA.
Mindy TsaiDepartment of Pathology and the Sean N. Parker Center for Allergy & Asthma Research, Stanford University School of Medicine, Stanford, CA, USA.
Stephen J GalliDepartment of Pathology and the Sean N. Parker Center for Allergy & Asthma Research, Stanford University School of Medicine, Stanford, CA, USA. sgalli@stanford.edu.ORCID http://orcid.org/0000-0001-5736-5340
Stanford University · USStanford Medicine · US

Funding

Stanford Center for Clinical & Translational Education and Research (Spectrum)UL1TR003142 · NCATS · STANFORD UNIVERSITY · PI O'HARA, RUTH M · 2019 to 2023
$45.0M
Spectrum Stanford Center for clinical and Translational Research and EducationUL1TR001085 · NCATS · STANFORD UNIVERSITY · PI CULLEN, MARK RICHARD, GREENBERG, HARRY BERNARD · 2013 to 2017
$37.1M
MOLECULAR &CELLULAR IMMUNOBIOLOGYT32AI007290 · NIAID · STANFORD UNIVERSITY · PI Sean Curtis Bendall, Olivia M Martinez · 1985 to 2026
$27.0M
Stanford Center for Clinical and Translational Education and Research (SCCTER)UL1UL1RR025744 · NCRR · STANFORD UNIVERSITY · PI GREENBERG, HARRY BERNARD · 2008 to 2011
$22.4M
Tracking allergen specific T cells in multi-food allergyU19AI104209 · NIAID · STANFORD UNIVERSITY · PI GALLI, STEPHEN JOSEPH · 2013 to 2025
$17.3M
Role of Mast Cells in Inflammation and ImmunityR01CA072074 · NCI · STANFORD UNIVERSITY · PI GALLI, STEPHEN JOSEPH · 1996 to 2010
$4.4M
Expression and Modulation of Mast Cell Function in AsthmaR01AI070813 · NIAID · STANFORD UNIVERSITY · PI GALLI, STEPHEN JOSEPH · 2006 to 2010
$2.5M
Regulation of Mast Cell Development and FunctionR01AI023990 · NIAID · STANFORD UNIVERSITY · PI GALLI, STEPHEN JOSEPH · 1986 to 2010
$2.4M
REGULATION OF MAST CELL DEVELOPMENT &FUNCTIONR37AI023990 · NIAID · STANFORD UNIVERSITY · PI GALLI, STEPHEN J · 1996 to 2005
$2.2M
RabGEF1 in MyD88 signaling, skin immunity, and atopic dermatitisR01AR067145 · NIAMS · STANFORD UNIVERSITY · PI GALLI, STEPHEN JOSEPH · 2015 to 2019
$1.9M
NCATS NIH HHS UL1 TR001085NCATS NIH HHS UL1 TR003142NCI NIH HHS R01 CA072074NCRR NIH HHS UL1 RR025744NIAID NIH HHS R01 AI023990NIAID NIH HHS R01 AI070813NIAID NIH HHS R37 AI023990NIAID NIH HHS T32 AI007290NIAID NIH HHS U19 AI104209NIAMS NIH HHS R01 AR067145
6 · The paper itself

Abstract

Mast cell-deficient mice are widely used to identify and quantify contributions of mast cells to diverse biological responses in vivo, including allergic inflammation. However, despite the fact that scores of genes have been identified as modifiers of allergic inflammation, most mast cell-deficient models have been available only on a single genetic background. We transferred the Kit

Indexed as

AsthmaDisease Models, AnimalAnimalsMast CellsMiceMice, Inbred BALB CMice, TransgenicProto-Oncogene Proteins c-kitProto-Oncogene Proteins c-kit

Identifiers

PMID31857699
PMCPMC7102933
OpenAlexW2996361241

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.