Evidence map›Paper›PMID 31857364›Full record

ArticleHaematologica2020

Activated protein C anticoagulant activity is enhanced by skeletal muscle myosin.

Mary J Heeb, José A Fernández, Atsuki Yamashita, Olivia R McDowell, Zihan Guo, Laurent O Mosnier, Hiroshi Deguchi, John H Griffin

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Haematologica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mary J HeebDepartment of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, USA heeb@scripps.edu jgriffin@scripps.edu.
José A FernándezDepartment of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, USA.
Atsuki YamashitaDepartment of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, USA.
Olivia R McDowellDepartment of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, USA.
Zihan GuoDepartment of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, USA.
Laurent O MosnierDepartment of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, USA.
Hiroshi DeguchiDepartment of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, USA.
John H GriffinDepartment of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, USA heeb@scripps.edu jgriffin@scripps.edu.

Funding

Regulation of Protein C PathwaysR01HL142975 · NHLBI · SCRIPPS RESEARCH INSTITUTE, THE · PI GRIFFIN, JOHN H, MOSNIER, LAURENT OLIVIER · 2018 to 2025
$7.3M
Novel functions of Thrombin Activatable Fibrinolysis Inhibitor (TAFI)R01HL148096 · NHLBI · SCRIPPS RESEARCH INSTITUTE, THE · PI MOSNIER, LAURENT OLIVIER · 2020 to 2023
$2.6M
Human exomics genotyping-driven discovery and characterization of proteins related to clinical thrombosis, blood coagulation and thrombin generationR01HL133728 · NHLBI · SCRIPPS RESEARCH INSTITUTE, THE · PI GRIFFIN, JOHN H · 2016 to 2019
$1.9M
NHLBI NIH HHS R01 HL133728NHLBI NIH HHS R01 HL148096
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Protein CSkeletal Muscle MyosinsActinsAnticoagulantsHumansMuscle, SkeletalMyosinsActinsAnticoagulantsMyosinsProtein CSkeletal Muscle Myosins

Identifiers

PMID31857364
PMCPMC7395292

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.