Evidence map›Paper›PMID 31857358›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2020

Brain-Derived Neurotrophic Factor Has a Transsynaptic Trophic Effect on Neural Activity in an Adult Forebrain Circuit.

Kimberly E Miller, William E Wood, Eliot A Brenowitz, David J Perkel

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Adult neurogenesis is necessary for functional regeneration of a forebrain neural circuit.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Kimberly E MillerDepartments of Psychology.ORCID 0000-0002-8858-3532
William E WoodNeuroscience Graduate Program, University of Washington, Seattle, Washington 98195-1800.
Eliot A BrenowitzDepartments of Psychology.
David J PerkelBiology, perkel@uw.edu.ORCID 0000-0002-3142-9614
Palmetto Hematology Oncology · USUniversity of Washington · US

Funding

Auditory Neuroscience Traning ProgramT32DC005361 · NIDCD · UNIVERSITY OF WASHINGTON · PI Adrian KC Lee, DAVID J PERKEL · 2002 to 2026
$8.8M
COMPARATIVE STUDIES OF VOCAL CONTROLR01MH053032 · NIMH · UNIVERSITY OF WASHINGTON · PI BRENOWITZ, ELIOT A · 1995 to 2015
$5.3M
Mechanisms of adult forebrain neural circuit regenerationR01NS103973 · NINDS · UNIVERSITY OF WASHINGTON · PI PERKEL, DAVID J · 2018 to 2022
$2.8M
NIDCD NIH HHS T32 DC005361NIMH NIH HHS R01 MH053032NINDS NIH HHS R01 NS103973
6 · The paper itself

Abstract

While hormone-driven plasticity in the adult brain is well studied, the underlying cellular and molecular mechanisms are less well understood. One example of this is seasonal plasticity in the avian brain, where song nuclei exhibit hormonally driven changes in response to changing photoperiod and circulating sex steroid hormones. Hormone receptor activation in song nucleus HVC (proper name) elicits a robust change in activity in target nucleus RA (robust nucleus of the arcopallium), but the molecular signal responsible for this is unknown. This study addressed whether brain-derived neurotrophic factor (BDNF) mediates a transsynaptic effect from HVC to RA in male Gambel's white-crowned sparrows (

Indexed as

AndrogensAnimalsBrain-Derived Neurotrophic FactorMaleNeural PathwaysNeuronal PlasticityPhotoperiodProsencephalonSparrowsTestosteroneAndrogensBrain-Derived Neurotrophic FactorTestosteronebreeding conditionneurotrophinseasonalsongbirdsteroidtranssynaptic

Identifiers

PMID31857358
PMCPMC7002143
OpenAlexW2995889818

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.