ArticleWorld journal of surgical oncology2019
Development and validation of a prognostic nomogram for predicting early recurrence after curative resection of stage II/III gastric cancer.
Article in World journal of surgical oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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11 citing papers in PubMed, 26 citations in OpenAlex.
- A deep learning-based digital biopsy for predicting early recurrence in gastric cancer.Nature communications · 2026Article
- Lymph Node Ratio as a Risk Factor for Early Recurrence in Older Patients with Stage II/III Gastric Cancer: A Retrospective Study.Journal of clinical medicine · 2025Article
- Impact of 5' Near Gene Variants of Mannose Binding Lectin (MBL2) on Breast Cancer Risk.Biochemical genetics · 2025Article
- Development of a Prognostic Nomogram for Overall Survival in Gastric Cancer Patients Who Underwent Adjuvant Chemoradiotherapy.Journal of gastrointestinal cancer · 2025Article
- Cost-utility of endoscopic screening strategies for upper gastrointestinal cancer across China: a modeling study.Frontiers in public health · 2025Article
- Risk factors for thyroid nodules in a health examination population: a cross-sectional study and development of a simplified predictive model.Frontiers in endocrinology · 2025Article
- A novel prognostic model to predict OS and DFS of stage II/III gastric adenocarcinoma patients in China.Heliyon · 2022Article
- Preoperative Low Prealbumin Is Associated With Recurrence in Patients With Stage II/III Gastric Cancer After Laparoscopic D2 Gastrectomy.Frontiers in surgery · 2022Article
- A nomogram to predict overall survival and disease-free survival after curative-intent gastrectomy for gastric cancer.Updates in surgery · 2021Article
- Development and Validation of a Radiomics Model Based onFrontiers in oncology · 2021Article
- A Novel Nutrition-Based Nomogram to Predict Prognosis After Curative Resection of Gastric Cancer.Frontiers in nutrition · 2021Article
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10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe biological behavior of early recurrence is more invasive and the prognosis is worse in gastric cancer (GC). The risk of early recurrence (ER) for GC in stage II/III has not been reported of which the majority of GC patients are in China. Therefore, it is necessary to analyze the ER of gastric cancer in stage II/III.
methodsThe medical records of 1511 consecutive stage II/III GC patients who received resections were retrospectively reviewed. They were randomly classified into either a development or validation group at a ratio of 7:3. The nomogram was constructed based on prognostic factors using logistic regression analysis and was validated by bootstrap resampling and validation dataset, respectively. Concordance index (C-index) values and calibration curves were used to evaluate the predictive accuracy and discriminatory capability.
resultsThree hundred eleven patients experienced ER, accounting for 20.58% of the GC patients investigated. Multivariate logistic regression analysis identified tumors located at upper, middle third, or mixed, a positive lymph node ratio ≥ 0.335, pTNM stage III, lymphocyte count < 1.5 × 10
conclusionsThe nomogram which was developed for predicting ER of stage II/III GC after surgery had good accuracy and was verified through both internal and external validation. The nomogram established can assist clinicians in determining the optimal therapy strategies in counseling, adjuvant treatments, and subsequent follow-up planning.
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