Evidence map›Paper›PMID 31856791›Full record

ArticleBMC pulmonary medicine2019

A web-based intervention to promote physical activity in adolescents and young adults with cystic fibrosis: protocol for a randomized controlled trial.

Narelle S Cox, Beverley Eldridge, Sarah Rawlings, Julianna Dreger, Jennifer Corda, Jennifer Hauser, Brenda M Button, Jennifer Bishop, Amanda Nichols, Anna Middleton and 10 more

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in BMC pulmonary medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04249999 (A Randomised Controlled Trial of a Novel Web-based Intervention to Promote Physical Activity Participation in People With Cystic Fibrosis), which is not on this map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04249999 nawithdrawnnot on this mapstarted 2020, after this paper: background citation

A Randomised Controlled Trial of a Novel Web-based Intervention to Promote Physical Activity Participation in People With Cystic Fibrosis

TypeinterventionalSponsorUniversity of ExeterRan2020 to 2021Enrolled0ConditionsCystic FibrosisArmsActivOnline
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. The 2025 European Cystic Fibrosis Society position statement on physical activity assessment in cystic fibrosis.European respiratory review : an official journal of the European Respiratory Society · 2025
    Guideline
  2. Physical activity and exercise training in cystic fibrosis.The Cochrane database of systematic reviews · 2022
    Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Sleep, Sedentary Time and Physical Activity Levels in Children with Cystic Fibrosis.International journal of environmental research and public health · 2022
    Article
  14. Article
  15. Article
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Narelle S CoxMonash University, La Trobe University and Institute for Breathing and Sleep, Level 6, The Alfred Centre, 99 Commercial Road, Melbourne, Vic, 3004, Australia. narelle.cox@monash.edu.
Beverley EldridgeLa Trobe University, Level 4, The Alfred Centre, 99 Commercial Road, Melbourne, Vic, 3004, Australia.
Sarah RawlingsMonash Children's Hospital Monash University and La Trobe University , 246 Clayton Rd, Clayton, Vic, 3168, Australia.
Julianna DregerMonash University, La Trobe University and Alfred Health, Level 6, The Alfred Centre, 99 Commercial Road, Melbourne, Vic 3004, Australia.
Jennifer CordaPhysiotherapy Department Royal Children's Hospital, 50 Flemington Road Parkville, Victoria, 3052, Australia.
Jennifer HauserTasmanian Adult Cystic Fibrosis Unit, Royal Hobart Hospital, GPO Box 1061, Hobart, Tasmania, 7000, Australia.
Brenda M ButtonDepartments of Physiotherapy and Respiratory Medicine Alfred Health and Department of Medicine, Nursing and Health Sciences, Monash University, 55 Commercial Road, Melbourne, Vic, 3004, Australia.
Jennifer BishopAdult Cystic Fibrosis Service, Westmead Hospital, PO Box 533, Wentworthville, NSW, 2145, Australia.
Amanda NicholsMonash Children's Hospital/Monash Health CF Service, 246 Clayton Rd, Clayton, Victoria, 3168, Australia.
Anna MiddletonPhysiotherapy Department, Children's Hospital at Westmead, Hawkesbury Road, Westmead, NSW, 2145, Australia.
Nathan WardPhysiotherapy and Cystic Fibrosis Services, 8E055.08, Royal Adelaide Hospital, Port Road, Adelaide, SA, 5000, Australia.
Tiffany DwyerDiscipline of Physiotherapy, Faculty of Health Sciences, The University of Sydney, PO Box 170, Lidcombe, NSW, 1825, Australia.
Owen W TomlinsonChildren's Health & Exercise Research Centre (CHERC), Sport and Health Sciences, College of Life and Environmental Sciences, St. Luke's Campus, University of Exeter, Heavitree Road, Exeter, Devon, EX1 2LU, UK.
Sarah DenfordChildren's Health & Exercise Research Centre (CHERC), Sport and Health Sciences, College of Life and Environmental Sciences, St. Luke's Campus, University of Exeter, Heavitree Road, Exeter, Devon, EX1 2LU, UK.
Alan R BarkerChildren's Health & Exercise Research Centre (CHERC), Sport and Health Sciences, College of Life and Environmental Sciences, St. Luke's Campus, University of Exeter, Heavitree Road, Exeter, Devon, EX1 2LU, UK.
Craig A WilliamsChildren's Health & Exercise Research Centre (CHERC), Sport and Health Sciences, College of Life and Environmental Sciences, St. Luke's Campus, University of Exeter, Heavitree Road, Exeter, Devon, EX1 2LU, UK.
Michael KingsleyLa Trobe Rural Health School, La Trobe University, Bendigo, Vic, 3552, Australia.
Paul O'HalloranSchool of Psychology and Public Health, La Trobe University, Bundoora, Vic, 3086, Australia.
Anne E HollandMonash University La Trobe University, Alfred Health and Institute for Breathing and Sleep, Level 6, The Alfred Centre, 99 Commercial Road, Melbourne, Vic, 3004, Australia.
Youth Activity Unlimited – A Strategic Research Centre of the UK Cystic Fibrosis Trust

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRegular participation in physical activity by people with cystic fibrosis (CF) promotes positive clinical and health outcomes including reduced rate of decline in lung function, fewer hospitalizations and greater wellbeing. However adherence to exercise and activity programs is low, in part due to the substantial daily therapy burden for young people with CF. Strict infection control requirements limit the role of group exercise programs that are commonly used in other clinical groups. Investigation of methods to promote physical activity in this group has been limited. The Active Online Physical Activity in Cystic fibrosis Trial (ActionPACT) is an assessor-blinded, multi-centre, randomized controlled trial designed to compare the efficacy of a novel web-based program (ActivOnline) compared to usual care in promoting physical activity participation in adolescents and young adults with CF.

methodsAdolescents and young adults with CF will be recruited on discharge from hospital for a respiratory exacerbation. Participants randomized to the intervention group will have access to a web-based physical activity platform for the 12-week intervention period. ActivOnline allows users to track their physical activity, set goals, and self-monitor progress. All participants in both groups will be provided with standardised information regarding general physical activity recommendations for adolescents and young adults. Outcomes will be assessed by a blinded assessor at baseline, after completion of the intervention, and at 3-months followup. Healthcare utilization will be assessed at 12 months from intervention completion. The primary outcome is change in moderate-to-vigorous physical activity participation measured objectively by accelerometry. Secondary outcomes include aerobic fitness, health-related quality of life, anxiety and depression and sleep quality. DISCUSSION: This trial will establish whether a web-based application can improve physical activity participation more effectively than usual care in the period following hospitalization for a respiratory exacerbation. The web-based application under investigation can be made readily and widely available to all individuals with CF, to support physical activity and exercise participation at a time and location of the user's choosing, regardless of microbiological status.

trial registrationClinical trial registered on July 13, 2017 with the Australian and New Zealand Clinical Trials Register at (ACTRN12617001009303).

Indexed as

ExerciseInternet-Based InterventionAccelerometryAdolescentAnxietyCystic FibrosisDepressionHumansPhysical FitnessQuality of LifeRandomized Controlled Trials as TopicSleepYoung AdultApplicationExerciseGoal settingOnlinePhysical fitnessTelerehabilitation

Identifiers

PMID31856791
PMCPMC6921562

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.