ArticleBMC nephrology2019
Intradialytic hypotension is an important risk factor for critical limb ischemia in patients on hemodialysis.
Article in BMC nephrology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 21 citations in OpenAlex.
- Intraprocedural Hemodynamics During Concomitant Rheocarna Therapy and Maintenance Hemodialysis: Effects of Dialyzer Membrane Type and Circuit Sequence.Journal of clinical apheresis · 2026Article
- Association of limb ischemic preconditioning with intradialytic hypotension in patients with diabetic kidney disease undergoing hemodialysis: a retrospective analysis.International urology and nephrology · 2026Article
- Identification of intradialytic hemodynamic phenotypes using latent profile analysis.Clinical kidney journal · 2026Article
- Investigation of the cleaning effect by the intermittent backfiltration in diafilters with polysulfone and polymethylmethacrylate membranes.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2026Article
- Impact of Chronic Limb-Threatening Ischemia in Patients on Hemodialysis.Journal of atherosclerosis and thrombosis · 2026Article
- The BestShape artificial intelligence system for real-time prediction of intradialytic hypotension-clinical outcomes after four-year follow-up.Clinical kidney journal · 2025Article
- Skin perfusion pressure in lower extremities at haemodialysis initiation is associated with 1-year mortality and cardiovascular disease.Clinical and experimental nephrology · 2025Article
- Association between intradialytic hypotension and physical function in patients undergoing maintenance hemodialysis: a multicenter cross-sectional study.Frontiers in medicine · 2025Article
- Association of frequent intradialytic hypotension with the clinical outcomes of patients on hemodialysis: a prospective cohort study.Renal failure · 2024Observational
- Impact of frequent intradialytic hypotension on quality of life in patients undergoing hemodialysis.BMC nephrology · 2023Article
- Associations of Iron Sucrose and Intradialytic Blood Pressure.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2023Article
- Association of chronic kidney disease with perioperative outcomes following acute lower limb revascularization.Surgery open science · 2022Article
- Intradialytic hypotension prediction using covariance matrix-driven whale optimizer with orthogonal structure-assisted extreme learning machine.Frontiers in neuroinformatics · 2022Article
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Authors and funding
9 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundCritical limb ischemia (CLI) and intradialytic hypotension (IDH) are common complications in patients on hemodialysis (HD). However, limited data are available on whether IDH is related to CLI in these patients. The aim of this retrospective study was to evaluate whether IDH is a risk factor for CLI in HD patients.
methodsWe examined the frequency of IDH in 147 patients who received HD between January 1 and June 30, 2012. Blood pressure was measured during HD every 30 min and IDH was defined as a ≥ 20 mmHg fall in systolic blood pressure compared to 30 min before and a nadir intradialytic systolic blood pressure < 90 mmHg. The primary study outcome was newly developed CLI requiring revascularization treatment or CLI-related death. We assessed the association of IDH with outcome using a multivariable subdistribution hazard model with adjustment for male, age, smoking and history of cardiovascular disease.
resultsThe median follow-up period was 24.5 months. Fifty patients (34%) had episodes of IDH in the study entry period. During follow-up, 14 patients received endovascular treatment and CLI-related death occurred in 1 patient. Factors associated with incident CLI in univariate analysis were age, smoking, diabetes mellitus, peripheral arterial disease, history of cardiovascular disease, and IDH. IDH was significantly associated with the outcome with the subdistribution hazard ratio of 3.13 [95% confidence interval, 1.05-9.37].
conclusionsIDH was an independent risk factor for incident CLI in patients on HD.
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