Evidence map›Paper›PMID 31856650›Full record

ArticleJournal of neurotrauma2020

Multi-Directional Dynamic Model for Traumatic Brain Injury Detection.

Kaveh Laksari, Michael Fanton, Lyndia C Wu, Taylor H Nguyen, Mehmet Kurt, Chiara Giordano, Eoin Kelly, Eoin O'Keeffe, Eugene Wallace, Colin Doherty and 6 more

Open access · greenAbstract read
In one paragraph

Article in Journal of neurotrauma, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Quantitative video analysis of head acceleration events: a review.Frontiers in bioengineering and biotechnology · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Finite element simulation of head impacts in mixed martial arts.Computer methods in biomechanics and biomedical engineering · 2021
    Article
  18. An Overview of the Effectiveness of Bicycle Helmet Designs in Impact Testing.Frontiers in bioengineering and biotechnology · 2021
    Review
  19. Article
  20. Low-Rank Representation of Head Impact Kinematics: A Data-Driven Emulator.Frontiers in bioengineering and biotechnology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 8 institutions in 3 countries.

Kaveh LaksariDepartment of Biomedical Engineering, University of Arizona, Tucson, Arizona.
Michael FantonDepartment of Mechanical Engineering, Stanford University, Stanford, California.
Lyndia C WuDepartment of Bioengineering, Stanford University, Stanford, California.
Taylor H NguyenDepartment of Bioengineering, Stanford University, Stanford, California.
Mehmet KurtDepartment of Bioengineering, Stanford University, Stanford, California.
Chiara GiordanoDepartment of Bioengineering, Stanford University, Stanford, California.
Eoin KellyDepartment of Neurology, Health Care Centre, Hospital 5, St James's Hospital, Dublin, Ireland.
Eoin O'KeeffeSmurfit Institute of Genetics, Trinity College Dublin, Dublin, Ireland.
Eugene WallaceDepartment of Neurology, Health Care Centre, Hospital 5, St James's Hospital, Dublin, Ireland.
Colin DohertyDepartment of Neurology, Health Care Centre, Hospital 5, St James's Hospital, Dublin, Ireland.
Matthew CampbellSmurfit Institute of Genetics, Trinity College Dublin, Dublin, Ireland.
Stephen TiernanDepartment of Mechanical Engineering, Technological University Dublin, Tallaght, Dublin, Ireland.
Gerald GrantDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, California.
Jesse RuanFord Motor Company, Dearborn, Michigan.
Saeed BarbatFord Motor Company, Dearborn, Michigan.
David B CamarilloDepartment of Biomedical Engineering, University of Arizona, Tucson, Arizona.
Stanford University · USSt. James's Hospital · IEFord Motor Company (United States) · USTrinity College Dublin · IEStevens Institute of Technology · USTechnological University Dublin · IEUniversity of Arizona · USUniversity of British Columbia · CA

Funding

Stanford Center for Clinical & Translational Education and Research (Spectrum)UL1TR003142 · NCATS · STANFORD UNIVERSITY · PI O'HARA, RUTH M · 2019 to 2023
$45.0M
Spectrum Stanford Center for clinical and Translational Research and EducationUL1TR001085 · NCATS · STANFORD UNIVERSITY · PI CULLEN, MARK RICHARD, GREENBERG, HARRY BERNARD · 2013 to 2017
$37.1M
Stanford Center for Clinical and Translational Education and Research (SCCTER)UL1UL1TR000093 · NCATS · STANFORD UNIVERSITY · PI GREENBERG, HARRY BERNARD · 2012 to 2013
$6.5M
NCATS NIH HHS UL1 TR000093NCATS NIH HHS UL1 TR001085NCATS NIH HHS UL1 TR003142
6 · The paper itself

Abstract

Given the worldwide adverse impact of traumatic brain injury (TBI) on the human population, its diagnosis and prediction are of utmost importance. Historically, many studies have focused on associating head kinematics to brain injury risk. Recently, there has been a push toward using computationally expensive finite element (FE) models of the brain to create tissue deformation metrics of brain injury. Here, we develop a new brain injury metric, the brain angle metric (BAM), based on the dynamics of a 3 degree-of-freedom lumped parameter brain model. The brain model is built based on the measured natural frequencies of an FE brain model simulated with live human impact data. We show that it can be used to rapidly estimate peak brain strains experienced during head rotational accelerations that cause mild TBI. In our data set, the simplified model correlates with peak principal FE strain (

Indexed as

Computer SimulationFinite Element AnalysisModels, NeurologicalBrain Injuries, TraumaticDatabases, FactualDiffusion Tensor ImagingHumansMalebrain injuryconcussioninjury criterioninjury prediction

Identifiers

PMID31856650
PMCPMC7175617
OpenAlexW2904603801

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.