Evidence map›Paper›PMID 31856608›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2020

Inhibition survey with phenolic compounds against the δ- and η-class carbonic anhydrases from the marine diatom

Siham A Alissa, Hanan A Alghulikah, Zeid A ALOthman, Sameh M Osman, Sonia Del Prete, Clemente Capasso, Alessio Nocentini, Claudiu T Supuran

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Introduction to Carbonic Anhydrase.Sub-cellular biochemistry · 2026
    Review
  3. Inhibition studies of the protozoan α-carbonic anhydrase fromJournal of enzyme inhibition and medicinal chemistry · 2022
    Article
  4. Surface display of carbonic anhydrase onSynthetic and systems biotechnology · 2022
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Siham A AlissaChemistry Department, College of Science, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.
Hanan A AlghulikahChemistry Department, College of Science, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.
Zeid A ALOthmanChemistry Department, College of Science, King Saud University, Riyadh, Saudi Arabia.
Sameh M OsmanChemistry Department, College of Science, King Saud University, Riyadh, Saudi Arabia.
Sonia Del PreteIstituto di Bioscienze e Biorisorse, CNR, Napoli, Italy.
Clemente CapassoIstituto di Bioscienze e Biorisorse, CNR, Napoli, Italy.ORCID http://orcid.org/0000-0003-3314-2411
Alessio NocentiniNEUROFARBA Department, Sezione di Scienze Farmaceutiche e Nutraceutiche, Sezione di Scienze Farmaceutiche e Nutraceutiche, Università degli Studi di Firenze, Sesto Fiorentino, Firenze, Italy.
Claudiu T SupuranNEUROFARBA Department, Sezione di Scienze Farmaceutiche e Nutraceutiche, Sezione di Scienze Farmaceutiche e Nutraceutiche, Università degli Studi di Firenze, Sesto Fiorentino, Firenze, Italy.ORCID http://orcid.org/0000-0003-4262-0323

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The inhibition of δ- and η-class carbonic anhydrases (CAs; EC 4.2.1.1) was poorly investigated so far. Only one δ-CA, TweCA from the diatom

Indexed as

Antiprotozoal AgentsCarbonic Anhydrase InhibitorsCarbonic AnhydrasesDiatomsDose-Response Relationship, DrugHumansMolecular StructureParasitic Sensitivity TestsPhenolsPlasmodium falciparumStructure-Activity RelationshipAntiprotozoal AgentsCarbonic Anhydrase InhibitorsCarbonic AnhydrasesPhenolsDiatominhibitionmetalloenzymeprotozoanδ-/η-class

Identifiers

PMID31856608
PMCPMC6968676

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.