Evidence map›Paper›PMID 31856537›Full record

ArticleIndian journal of ophthalmology2020

Rheumatoid factor versus anti - cyclic citrullinated peptide antibody as screening tool for rheumatoid arthritis in an ophthalmic clinic.

Prabhakar Singh, Arvind Kumar, Prakash Chandra

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Indian journal of ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 76% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Prabhakar SinghHead of Cornea and Anterior Segment Services, Nirwana Netralaya, Sasaram, Rohtas, Bihar, India.
Arvind KumarHead of Occuloplasty Services, Nirwana Netralaya, Sasaram, Rohtas, Bihar, India.
Prakash ChandraNirwana Netralaya, Sasaram, Rohtas, Bihar, India.
Christie's · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with moderate to severe dry eyes are often screened at the Dry Eye Clinic to rule out connective tissue diseases. Rheumatoid factor (RF) is one of the screening tools to rule out rheumatoid arthritis (RA). Patients who turn out positive for the RF are often subjected to anti-CCP antibody evaluation for confirmation of disease. This article tries to highlight 3 cases of negative and anti-CCP antibody positive cases which presented to the ophthalmic clinic, unaware of their systemic status. Though RF is the cheapest modality to screen for RA, it is not always a reliable marker. One should order anti-CCP antibody for patients where suspicion is high, despite RF being normal.

Indexed as

Arthritis, RheumatoidBiomarkersDry Eye SyndromesEnzyme-Linked Immunosorbent AssayFemaleHumansMaleMiddle AgedPeptides, CyclicRheumatoid FactorBiomarkerscyclic citrullinated peptidePeptides, CyclicRheumatoid FactorAnti-CCP antibodyophthalmic clinicRheumatoid factor

Identifiers

PMID31856537
PMCPMC6951140
OpenAlexW2995785258

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.