Evidence map›Paper›PMID 31856472›Full record

Observational studyIndian journal of ophthalmology2020

Corneal endothelial cell changes in diabetics versus age group matched nondiabetics after manual small incision cataract surgery.

Ajay A Kudva, Adeline S Lasrado, Sudhir Hegde, Rajani Kadri, P Devika, Akansha Shetty

Abstract readComparative StudyObservational Study
In one paragraph

Observational study in Indian journal of ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Complications of manual small-incision cataract surgery.Indian journal of ophthalmology · 2022
    Review
  6. Observational
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Ajay A KudvaDepartment of Ophthalmology, A. J. Institute of Medical Sciences and Research Center, Kuntikana, Mangalore, Karnataka, India.
Adeline S LasradoDepartment of Ophthalmology, A. J. Institute of Medical Sciences and Research Center, Kuntikana, Mangalore, Karnataka, India.
Sudhir HegdeDepartment of Ophthalmology, A. J. Institute of Medical Sciences and Research Center, Kuntikana, Mangalore, Karnataka, India.
Rajani KadriDepartment of Ophthalmology, A. J. Institute of Medical Sciences and Research Center, Kuntikana, Mangalore, Karnataka, India.
P DevikaDepartment of Ophthalmology, A. J. Institute of Medical Sciences and Research Center, Kuntikana, Mangalore, Karnataka, India.
Akansha ShettyDepartment of Ophthalmology, A. J. Institute of Medical Sciences and Research Center, Kuntikana, Mangalore, Karnataka, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To assess and compare the endothelial cell changes after manual small incision cataract surgery (SICS) in diabetic patients versus age group matched non-diabetic patients. Methods: This comparative prospective observational follow-up study included 54 diabetic patients and 52 control patients without diabetes who underwent manual SICS. Preoperative, one day, one week, one month and three months post-surgery assessments of corneal endothelial cell changes were done using specular microscopy. Data analysis was performed using SPSS software (version 20.0, SPSS, Inc.). Mann-Whitney U test was used to compare the data between the test group and control group. Results: There was drop in the endothelial density in both the groups postoperatively, with the mean percentage of endothelial loss at three months post- surgery being 27.5% in diabetics and 18.3% in controls. There was also a significant increase in central corneal thickness and coefficient of variance in diabetics as compared to controls at every follow up one day, one week, one month and three months. The percentage of hexagonality was statistically significant at post-operative three months. Conclusion: The diabetic endothelium was found to be under greater metabolic stress and had less functional reserve after manual SICS than the normal corneal endothelium.

Indexed as

Diabetes MellitusPostoperative ComplicationsAgedAged, 80 and overCataractCorneal Endothelial Cell LossEndothelium, CornealFemaleFollow-Up StudiesHumansMaleMicrosurgeryMiddle AgedPhacoemulsificationPostoperative PeriodProspective StudiesDiabetes mellitusEndothelial cell lossSmall incision Cataract surgery

Identifiers

PMID31856472
PMCPMC6951183

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.