ReviewIndian journal of ophthalmology2020
Management of corneal perforations: An update.
Review in Indian journal of ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07440186 (Exploratory Clinical Research for the Evaluation of Human GMP Collagen Implants), which is not on this map. Cited by 65 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Exploratory Clinical Research for the Evaluation of Human GMP Collagen Implants (Humabiologics) in the Treatment of Corneal Melting.
Who cites it
65 citing papers in PubMed, 1 synthesis or guideline pooled it, 130 citations in OpenAlex.
- Management of corneal perforations in dry eye disease: Preferred practice pattern guidelines.Indian journal of ophthalmology · 2023Guideline
- Therapeutic penetrating keratoplasty for recalcitrant microbial keratitis: An update.World journal of transplantation · 2026Review
- Clinical Characteristics, Management, and Visual Outcomes of Spontaneous Corneal Perforation: A Single-Center Retrospective Study in South Korea.Korean journal of ophthalmology : KJO · 2026Article
- Anterior segment optical coherence tomography-guided assessment of wound healing after cyanoacrylate glue patch for corneal perforations.Indian journal of ophthalmology · 2026Article
- Elderly Male with a Painful Red Eye.Clinical practice and cases in emergency medicine · 2026Article
- A Practical Approach to Corneal Perforation in the Absence of Donor Tissue.Annals of African medicine · 2026Article
- Hyaluronic Acid-Based Photocurable Glue Application as an Alternative Surgical Approach for Corneal Injuries in Canine Patients: A Case Series.Veterinary medicine and science · 2026Article
- Deep Learning for the Detection of Corneal Perforation on Anterior-Segment Optical Coherence Tomography in Microbial Keratitis.Bioengineering (Basel, Switzerland) · 2026Article
- Surgical Management of Corneal Damage in Patients with Primary and Post-Surgical Eyelid Anomalies.Journal of clinical medicine · 2026Review
- Corneal thinning and perforation: a narrative review of diagnostic and stepwise management strategies.International ophthalmology · 2026Review
- Full-Thickness Corneal Perforation Secondary to Monopolar Cautery Burn During Cosmetic Blepharoplasty in a Young Adult: Successful Management With Cyanoacrylate Glue.Clinical case reports · 2026Article
- Comparative effectiveness of penetrating keratoplasty and conservative cyanoacrylate tissue adhesive application for corneal perforation and thinning.Eye (London, England) · 2026Article
- What We Can Do in Infectious Keratitis, Except for Conventional Antimicrobial-Based Therapies: Major Narrative Review.Health science reports · 2026Article
- Next-generation smart ophthalmic biomaterials: From passive response to active interaction and closed-loop control.Bioactive materials · 2026Review
- Photochemical-Tissue Bonding Toward a More Effective Strategy for Corneal Epithelial Healing after Alkali Burn.Journal of ophthalmic & vision research · 2026Article
- Combined PRP and Contact Lens for Corneal Ulcer Perforation: A Case Report.International medical case reports journal · 2026Article
- Photocrosslinked dual-network hydrogel for sutureless corneal stromal lenticule lmplantation.Frontiers in bioengineering and biotechnology · 2026Article
- Sutureless Amniotic Membrane Grafting in the Management of Corneal Perforations Associated with Severe Ocular Surface Disease.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
- "Pocket" technique: a multiple-layer amniotic membrane transplant approach for managing graft-versus-host disease-associated corneal perforations.International journal of ophthalmology · 2026Article
- Multilayered amniotic membrane transplantation for tectonic stabilization and symptomatic relief in pediatric post-traumatic corneal thinning: a case report.Medical hypothesis, discovery & innovation ophthalmology journal · 2026Article
5 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Corneal perforation is a potentially devastating complication that can result from numerous conditions that precipitate corneal melting. It is associated with significant morbidity and prompt intervention is necessary to prevent further complications. Causes include microbial keratitis, ocular surface disease, and autoimmune disorders and trauma. Various management options have been described in the literature to facilitate visual rehabilitation. This rview discusses the treatment options that range from temporising measures such as corneal gluing through to corneal transplantation, with decision making guided by the location, size, and underlying aetiology of the perforation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.