Evidence map›Paper›PMID 31856430›Full record

ArticlePediatric obesity2020

Parental adiposity differentially associates with newborn body composition.

Eva C Diaz, Mario A Cleves, Marisha DiCarlo, Sarah R Sobik, Meghan L Ruebel, Keshari M Thakali, Clark R Sims, Nafisa K Dajani, Rebecca A Krukowski, Elisabet Børsheim and 3 more

Open access · greenAbstract read
In one paragraph

Article in Pediatric obesity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 3 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 3 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Association between maternal adiposity measures and infant health outcomes: A systematic review and meta-analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2022
    Pooled it
  3. Physical Activity during Pregnancy and Newborn Body Composition: A Systematic Review.International journal of environmental research and public health · 2022
    Pooled it
  4. Trial
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  12. Body Composition Measurements from Birth through 5 Years: Challenges, Gaps, and Existing & Emerging Technologies-A National Institutes of Health workshop.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2020
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Eva C DiazArkansas Children's Nutrition Center, Little Rock, Arkansas.ORCID 0000-0002-3528-677X
Mario A ClevesArkansas Children's Nutrition Center, Little Rock, Arkansas.
Marisha DiCarloArkansas Children's Nutrition Center, Little Rock, Arkansas.
Sarah R SobikDepartment of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas.
Meghan L RuebelArkansas Children's Nutrition Center, Little Rock, Arkansas.
Keshari M ThakaliArkansas Children's Nutrition Center, Little Rock, Arkansas.
Clark R SimsArkansas Children's Nutrition Center, Little Rock, Arkansas.
Nafisa K DajaniDepartment of Obstetrics and Gynecology, University of Arkansas for Medical Sciences, Little Rock, Arkansas.
Rebecca A KrukowskiArkansas Children's Nutrition Center, Little Rock, Arkansas.
Elisabet BørsheimArkansas Children's Nutrition Center, Little Rock, Arkansas.
Thomas M BadgerArkansas Children's Nutrition Center, Little Rock, Arkansas.
Kartik ShankarArkansas Children's Nutrition Center, Little Rock, Arkansas.
Aline AndresArkansas Children's Nutrition Center, Little Rock, Arkansas.ORCID 0000-0003-2611-2193
Arkansas Children's Nutrition Center · USArkansas Children's Hospital · USUniversity of Arkansas for Medical Sciences · US

Funding

The Role of the Mitochondrion in the Metabolic Stress Response to Burn TraumaP20GM109096 · NIGMS · ARKANSAS CHILDREN'S HOSPITAL RES INST · PI PORTER, CRAIG · 2016 to 2025
$20.7M
Phenotypic and metabolic characteristics in early childhood leading to obesityR01DK107516 · NIDDK · ARKANSAS CHILDREN'S HOSPITAL RES INST · PI ANDRES, ALINE, BORSHEIM, ELISABET · 2016 to 2020
$1.6M
NIDDK NIH HHS R01 DK107516NIGMS NIH HHS P20 GM109096
6 · The paper itself

Abstract

backgroundMaternal obesity increases offspring's obesity risk. However, studies have not often considered maternal metabolic and exercise patterns as well as paternal adiposity as potential covariates.

objectiveTo assess the relationship between parental and newborn adiposity.

methodsParticipants were mother-child pairs (n = 209) and mother-father-offspring triads (n = 136). Parental (during gestation) and offspring (2 weeks old) percent fat mass (FM) were obtained using air displacement plethysmography. Maternal race, age, resting energy expenditure (indirect calorimetry), physical activity (accelerometry), gestational weight gain (GWG), gestational age (GA), delivery mode, infant's sex and infant feeding method were incorporated in multiple linear regression analyses. The association between parental FM and offspring insulin-like growth factor 1 (IGF-1) was assessed at age 2 years.

resultsMaternal adiposity was positively-associated with male (β = 0.11, P = .015) and female (β = 0.13, P = .008) infant FM, whereas paternal adiposity was negatively-associated with male newborn adiposity (β = -0.09, P = .014). Breastfeeding, female sex, GA and GWG positively associated with newborn adiposity. Vaginal and C-section delivery methods associated with greater adiposity than vaginal induced delivery method. Plasma IGF-1 of 2-year-old boys and girls positively associated with their respective fathers' and mothers' FM.

conclusionsMaternal and paternal adiposity differentially associate with newborn adiposity. The mechanisms of this finding remain to be determined.

Indexed as

AdiposityBody CompositionParentsAdultChild, PreschoolFemaleGestational AgeHumansInfant, NewbornInsulin-Like Growth Factor IMalePregnancyWeight GainInsulin-Like Growth Factor Ibody compositionfoetal programminggrowth hormoneobesitypregnancy

Identifiers

PMID31856430
PMCPMC7367307
OpenAlexW2995534081

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.