Evidence map›Paper›PMID 31856341›Full record

ArticleInfluenza and other respiratory viruses2020

Persistence of H7N9 virus antibody response 2 years after infection.

Lin Yao, Guo-Lin Wang, Li-Ling Chen, Cheng Liu, Li-Jun Duan, Gregory C Gray, Mai-Juan Ma

Abstract read
In one paragraph

Article in Influenza and other respiratory viruses, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Persistence of H7N9 virus antibody response 2 years after infection.Influenza and other respiratory viruses · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lin YaoState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China.
Guo-Lin WangState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China.
Li-Ling ChenSuzhou Municipal Center for Disease Control and Prevention, Suzhou, China.
Cheng LiuSuzhou Municipal Center for Disease Control and Prevention, Suzhou, China.
Li-Jun DuanState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China.
Gregory C GrayDivision of Infectious Diseases, School of Medicine, Global Health Institute, Duke University, Durham, North Carolina.ORCID 0000-0002-4628-5908
Mai-Juan MaState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China.ORCID 0000-0002-8105-462X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We measured antibodies against H7N9 virus 2 years after infection in 14 patients who were infected during October 2016-September 2017. Approximately 2 years after infection, antibody titers ≥10 were detectable in 13 (92.9%) patients. Three (21.4%) of 14 patients had hemagglutination inhibition titers ≥40, and their geometric mean titer (GMT) was 20 (95% CI 15.7-28.1), whereas 10 (71.4%) and all 14 (100%) of the 14 patients had titers ≥40, and GMTs at 34.4 (95% CI 25.7-51.2) and 73.45 (54.7-106.7) for neuraminidase inhibition and microneutralization antibodies, respectively. Our findings suggest that H7N9 infection may induce long-term antibody response at least 2 years after infection.

Indexed as

Antibody FormationAdultAgedAntibodies, ViralFemaleFollow-Up StudiesHemagglutination Inhibition TestsHumansInfluenza A Virus, H7N9 SubtypeInfluenza, HumanMaleMiddle AgedAntibodies, Viralantibody responseH7N9 virusesinfluenza A viruspersistenceserological

Identifiers

PMID31856341
PMCPMC7040969

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.