ArticleAddictive behaviors2020
Childhood adversity and mental health comorbidity in men and women with opioid use disorders.
Article in Addictive behaviors, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
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Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.
- Prevalence of childhood maltreatment among people with opioid use disorder: A systematic review and meta-analysis.Drug and alcohol dependence · 2021Pooled it
- Psychiatric comorbidity and treatment outcomes in patients with opioid use disorder: Results from a multisite trial of buprenorphine-naloxone and methadone.Drug and alcohol dependence · 2021Trial
- Long-Acting Injectable Buprenorphine in Prison: Insights From a Short-Answer Survey of People in the Criminal Justice System Commencing Long-Acting Injectable Buprenorphine During a Non-Randomised Clinical Trial.Drug and alcohol review · 2026Article
- Bullying Victimisation and Mental Health: The Mediating Role of Peer and Family Social Support.Early intervention in psychiatry · 2026Article
- Estimated Prevalence of Current Posttraumatic Stress Disorder Among Pregnant Women With Opioid Use Disorder-MATernaL and Infant Clinical NetworK (MAT-LINK), 2014-2021.Journal of addiction medicine · 2026Article
- Trauma-informed psychological support alongside long-acting injectable buprenorphine: clients' perspectives on the Buvidal psychological support service (BPSS) pilot in Wales.Frontiers in psychiatry · 2026Article
- The Role of Child Maltreatment and Revictimization on Substance Use Trajectories Among Women Involved in the Criminal Justice System.Women & criminal justice · 2025Article
- Gender and Overdose Risk Factors Among Clients Entering Residential Treatment for Opioid Use.Drug and alcohol review · 2025Article
- State sequence analysis of daily methadone dispensing trajectories among individuals at United States opioid treatment programs before and following COVID-19 onset.Addiction (Abingdon, England) · 2025Article
- Associations of childhood adversity and substance use disorder polygenic scores with disorder severity and diagnostic criteria.Psychological medicine · 2025Article
- Integration of Peer Navigators Into Longitudinal Research.Journal of obstetric, gynecologic, and neonatal nursing : JOGNN · 2025Observational
- Article
- The lived experiences and treatment needs of women with opioid use disorder and posttraumatic stress symptoms: A mixed methods study.Journal of substance use and addiction treatment · 2024Article
- Maltreatment, resilience, and sexual relationship power in a sample of justice-involved women with opioid use disorder.Journal of traumatic stress · 2024Article
- Neuroendocrine mechanisms in the links between early life stress, affect, and youth substance use: A conceptual model for the study of sex and gender differences.Frontiers in neuroendocrinology · 2024Review
- Psychological distress among postpartum women who took opioids during pregnancy: the role of perceived stigma in healthcare settings.Archives of women's mental health · 2024Article
- Overdose Experiences Among a Sample of Women in Jail with Opioid Use Disorder.Substance use & misuse · 2024Article
- Are adverse childhood experiences associated with trajectories of healthy aging? Evidence from China.SSM - population health · 2023Article
- Weight change among patients engaged in medication treatment for opioid use disorder: a scoping review.The American journal of drug and alcohol abuse · 2023Article
- Prevalence of Childhood Trauma in a Community-Based Mental Health Clinic.Community mental health journal · 2023Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
introductionTo examine gender differences in associations between mental health comorbidity and adverse childhood experiences (ACE) among adults with DSM-5 lifetime opioid use disorders (OUD).
methodsIn 2018, we analyzed 2012-13 nationally-representative data from 388 women and 390 men with OUD (heroin, prescription opioid misuse). Using weighted multinomial logistic regression, we examined factors associated with mental health comorbidity, tested a gender-by-childhood-adversity interaction term, and calculated predicted probabilities, controlling for covariates.
resultsAmong adults with OUD, women are more likely than men to have comorbid mood or anxiety disorders (odds ratio [95% CI] 1.72 [1.20, 2.48]), and less likely to have conduct disorders. More women than men have prescription OUD (3.72 [2.24, 6.17]), and fewer have heroin use disorder (0.39 [0.27, 0.57]). Among both genders, ACE prevalence is high (>80%) and more than 40% are exposed to ≥3 types of ACE. Women more than men are exposed to childhood sexual abuse (4.22 [2.72, 6.56]) and emotional neglect (1.84 [1.20, 2.81]). Comorbid mood or anxiety disorders are associated with female gender (1.73 [1.18, 2.55]) and exposure to ≥3 types of ACE (3.71 [2.02, 6.85]), controlling for covariates. Moreover, exposure to more ACE elevates risk for comorbid mood or anxiety disorders more among women than men.
conclusionAmong adults with OUD, ACE alters the gender gap in risk for comorbid mood or anxiety disorders. Using gender-tailored methods to address the harmful effects ACE on the mental health of individuals with OUD may help to prevent and ameliorate the current opioid epidemic.
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Registered trials
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