ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2019
Factors Influencing the Presentation of REM Sleep Behavior Disorder: The Relative Importance of Sex, Associated Neurological Disorder, and Context of Referral to Polysomnography.
Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Sex differences in alpha-synucleinopathies: a systematic review.Frontiers in neurology · 2023Pooled it
- Antidepressant medications have differential effects on REM sleep without atonia quantified by chin and upper extremity EMG.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026Article
- Isolated REM Sleep Behaviour Disorder-Is Screening Possible?Journal of sleep research · 2025Review
- Gender Difference in REM Sleep Behavior Disorder in Japanese Population: Polysomnography and Sleep Questionnaire Study.Journal of clinical medicine · 2024Article
- Neurofilament light chain and cardiac MIBG uptake as predictors for phenoconversion in isolated REM sleep behavior disorder.Journal of neurology · 2023Article
- Sex differences in dementia with Lewy bodies: Focused review of available evidence and future directions.Parkinsonism & related disorders · 2023Review
- The Accuracy and Reliability of Sleep Staging and Sleep Biomarkers in Patients with Isolated Rapid Eye Movement Sleep Behavior Disorder.Nature and science of sleep · 2023Article
- Rapid eye movement sleep behaviour disorder: Past, present, and future.Journal of sleep research · 2022Review
- The temporal onset of the core features in dementia with Lewy bodies.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2022Article
- REM sleep absence in patients referred to polysomnography for REM sleep behavior disorder.Journal of neural transmission (Vienna, Austria : 1996) · 2021Article
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2 authors.
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Abstract
STUDY
objectivesTo identify the interrelation and relative influence of sex, associated neurological disorder, and polysomnography (PSG) context on the manifestations of rapid eye movement (REM) sleep behavior disorder (RBD).
methodsFifty-seven patients with RBD were assessed with video PSG regarding sleep structure, muscular activity, and motor events (ME) during REM sleep. Patients were categorized according to sex, associated neurological disorder (clinically isolated RBD [iRBD] versus RBD associated with an overt α-synucleinopathy [sRBD]) and motive for PSG (direct referral due to RBD symptoms [First, n = 14]; referred after screening procedures [Screening, n = 13]; referred during clinical follow-up for other disorders [Follow-up, n = 22]; referred for symptoms other than RBD [Incidental, n = 8]).
resultsPhasic muscular activity index and the relative number of myoclonic and trunk ME were significantly higher in males and segmental ME in female patients. sRBD was associated with Screening and iRBD with First categories. There was a higher severity of ME in patients with iRBD. Global motor severity of ME was significantly higher in the First category. In multivariate analysis, both motive for PSG and associated neurological disorder had a significant and independent influence in the global severity of ME.
conclusionsAssociated neurological disorder and motive for PSG can significantly influence RBD presentation. Male sex is related with higher muscular phasic activity and a different pattern of ME, which could contribute to prevalence variations across studies. Having iRBD and being directly referred for a first consultation because of complaints compatible with RBD are interrelated and contribute independently to a higher severity of ME.
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