Evidence map›Paper›PMID 31855136›Full record

ArticleEmerging infectious diseases2020

Candidatus Mycoplasma haemohominis in Human, Japan.

Norimichi Hattori, Makoto Kuroda, Harutaka Katano, Takahiro Takuma, Takayoshi Ito, Nana Arai, Ryo Yanai, Tsuyoshi Sekizuka, Sho Ishii, Yoko Miura and 8 more

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Emerging infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Molecular detection and genetic diversity of hemotropicCurrent research in parasitology & vector-borne diseases · 2026
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  8. Molecular survey of Bartonella spp., Ehrlichia spp., Anaplasma spp. and hemoplasmas in small synanthropic mammals in urban areas of Brazil's northern Amazon region.Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria · 2025
    Article
  9. Molecular detection of hemoplasmas in domestic cats from different Brazilian regions.Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 2 institutions in 1 country.

Norimichi Hattori
Makoto Kuroda
Harutaka Katano
Takahiro Takuma
Takayoshi Ito
Nana Arai
Ryo Yanai
Tsuyoshi Sekizuka
Sho Ishii
Yoko Miura
Takahiro Tokunaga
Hiroyuki Watanabe
Norihiro Nomura
Junichi Eguchi
Hideki Hasegawa
Tsuyoshi Nakamaki
Takaji Wakita
Yoshihito Niki
National Institute of Infectious Diseases · JPShowa University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hemotropic mycoplasmas are common pathogens in animals, but it remains unclear what role these pathogens play in human infections. We report clinical and biologic characterization of Candidatus Mycoplasma haemohominis infection in a 42-year-old man in Japan. The patient had severe hemophagocytic syndrome 1 month after an accidental needlestick injury. Metagenomic deep sequencing identified Candidatus M. haemohominis and determined its draft genome for an isolate from serum of the patient. A high copy number of the Candidatus M. haemohominis genome was detected in serum and bone marrow samples. Electron microscopy examination showed morphologic characteristics of Candidatus M. haemohominis. Levofloxacin monotherapy induced resistance caused by a gyrase A gene mutation in the quinolone resistance-determining region, but a combination treatment with moxifloxacin and minocycline was effective. We identified Candidatus M. haemohominis in a patient who had life-threatening symptoms related to multiple organ infection. Human infection with this mycoplasma might occur more frequently than has been generally recognized.

Indexed as

MycoplasmaAdultErythemaHigh-Throughput Nucleotide SequencingHumansJapanMaleMicroscopy, ElectronMycoplasma InfectionsPruritusSkinbacteriaCandidatus Mycoplasma haemohominishemophagocytic syndromehemoplasmahuman infectionJapanmetagenomicsmycoplasma

Identifiers

PMID31855136
PMCPMC6924906
OpenAlexW2993952308

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.