Evidence map›Paper›PMID 31855059›Full record

ArticleJournal of computational biology : a journal of computational molecular cell biology2020

Minimization-Aware Recursive

Jonathan D Jou, Graham T Holt, Anna U Lowegard, Bruce R Donald

Abstract read
In one paragraph

Article in Journal of computational biology : a journal of computational molecular cell biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Protocol for DesigningJournal of computational biology : a journal of computational molecular cell biology · 2024
    Article
  2. DexDesign: an OSPREY-based algorithm for designing de novo D-peptide inhibitors.Protein engineering, design & selection : PEDS · 2024
    Article
  3. RESISTOR: A New OSPREY Module to Predict Resistance Mutations.Journal of computational biology : a journal of computational molecular cell biology · 2022
    Article
  4. Article
  5. Article
  6. Article
  7. Minimization-Aware RecursiveJournal of computational biology : a journal of computational molecular cell biology · 2020
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jonathan D JouDepartment of Computer Science, Duke University, Durham, North Carolina.
Graham T HoltDepartment of Computer Science, Duke University, Durham, North Carolina.
Anna U LowegardDepartment of Computer Science, Duke University, Durham, North Carolina.
Bruce R DonaldDepartment of Computer Science, Duke University, Durham, North Carolina.

Funding

Computational Structure-Based Protein DesignR01GM078031 · NIGMS · DUKE UNIVERSITY · PI DONALD, BRUCE R. · 2008 to 2021
$4.3M
Deep Topological Sampling of Protein StructuresR01GM118543 · NIGMS · DUKE UNIVERSITY · PI DONALD, BRUCE R. · 2017 to 2020
$1.4M
NIGMS NIH HHS R01 GM078031NIGMS NIH HHS R01 GM118543
6 · The paper itself

Abstract

Protein design algorithms that model continuous sidechain flexibility and conformational ensembles better approximate the

Indexed as

Computational BiologyProtein ConformationSoftwareAlgorithmsAmino Acid SequenceEntropyModels, MolecularProtein DomainsProteinsThermodynamicsProteinscomputational protein designenergy landscapesK*OSPREYpartition functionprovable algorithmsthermodynamics

Identifiers

PMID31855059
PMCPMC7185359

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.