Evidence map›Paper›PMID 31853902›Full record

ArticlePlant foods for human nutrition (Dordrecht, Netherlands)2020

Antihypertensive Effect and Safety Evaluation of Rice Bran Hydrolysates from Sang-Yod Rice.

Gulladawan Jan-On, Weerapon Sangartit, Poungrat Pakdeechote, Veerapol Kukongviriyapan, Ketmanee Senaphan, Orachorn Boonla, Chakree Thongraung, Upa Kukongviriyapan

Abstract read
PubMed Publisher
In one paragraph

Article in Plant foods for human nutrition (Dordrecht, Netherlands), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Gulladawan Jan-OnDepartment of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand.
Weerapon SangartitDepartment of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand.
Poungrat PakdeechoteDepartment of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand.
Veerapol KukongviriyapanDepartment of Pharmacology, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand.
Ketmanee SenaphanDivision of Physiology, Faculty of Veterinary Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand.
Orachorn BoonlaFaculty of Allied Health Sciences, Burapha University, Chonburi, 20131, Thailand.
Chakree ThongraungDepartment of Food Technology, Faculty of Agro-Industry, Prince of Songkla University, Songkla, 90112, Thailand.
Upa KukongviriyapanDepartment of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand. upa_ku@kku.ac.th.
Khon Kaen University · THBurapha University · THPrince of Songkla University · TH

Funding

National Research Council of Thailand CRP5507020810
6 · The paper itself

Abstract

Rice bran hydrolysates contain highly nutritional proteins and beneficial phytochemicals. Sang-Yod rice bran hydrolysates (SRH) extracted from red pigmented rice is a rich source of nutrients and phenolic compounds. The present study evaluated the antihypertensive effect of SRH and its safety in Sprague-Dawley rats. Hypertension was induced in male rats by administration of L-NAME (50 mg/kg/day) in drinking water for three weeks, and the antihypertensive effect of SRH was evaluated. Treatment of SRH (250 or 500 mg/kg) significantly reduced arterial blood pressure and improved hemodynamic parameters. The antihypertensive effect was associated with decreased oxidative stress, suppressed p47

Indexed as

HypertensionOryzaAnimalsAntihypertensive AgentsBlood PressureFemaleMaleNG-Nitroarginine Methyl EsterNitric OxideOxidative StressRatsRats, Sprague-DawleyAntihypertensive AgentsNG-Nitroarginine Methyl EsterNitric OxideHypertensionL-NAMENitric oxideOxidative stressSang-Yod rice bran hydrolysatesSubchronic toxicity

Identifiers

PMID31853902
OpenAlexW2996458727

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.